cas 189281-61-6, 4-Pyridinamine,2,5-difluoro-(9CI) | Articles data ｜lookchem

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189281-61-6

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Direct SNAr amination of fluorinated imidazo[4,5-c]pyridine nucleosides: Efficient syntheses of 3-fluoro-3-deazaadenosine analogs
This paper describes the ready preparation of 3,6-difluoro-3-deazapurine (4,7-difluoroimidazo[4,5-c]pyridine). This novel base was glycosylated under mild conditions using three different ribose sugar analogs. 3,6-Difluoro-3- deazapurine ribonucleoside an
Sakthivel, Kandasamy,Cook, P. Dan
p. 3883 - 3887
(2007/10/03)

A new approach to polyfluoroaromatic amines with an unsubstituted position ortho to the amino group
N-acetyl derivatives of polyfluoroaromatic amines have been found to be highly selectively defluorinated by zinc in aqueous ammonia at the position ortho to the acetamido group thus affording a new approach to potential building blocks for the synthesis o
Laev,Evtefeev,Shteingarts
p. 43 - 46
(2007/10/03)

Pyridonecarboxylic acid derivatives or their salts and antibacterial agent comprising the same as the active ingredient
A pyridonecarboxylic acid derivative represented by the following general formula (1): STR1 [wherein R1 represents hydrogen atom or a carboxyl protective group; R2 represents hydroxyl group, a lower alkoxy group, or a substituted or unsubstituted amino group; R3 represents hydrogen atom or a halogen atom; R4 represents hydrogen atom or a halogen atom; R5 represents a halogen atom or an optionally substituted saturated cyclic amino group; R6 represents hydrogen atom, a halogen atom, nitro group, or an optionally protected amino group; X, Y and Z may be the same or different and respectively represent nitrogen atom, --CH= or --CR7 = (wherein R7 represents a lower alkyl group, a halogen atom, or cyano group) (with the proviso that at least one of X, Y and Z represent the nitrogen atom), and W represents nitrogen atom or --CR8 = (wherein R8 represents hydrogen atom, a halogen atom, or a lower alkyl group)] or its salt, as well as an antibacterial agent containing such compound are provided.
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(2008/06/13)

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Chemical Properties

Boiling Point: 237.4±35.0 °C(Predicted)
Density: 1.393±0.06 g/cm3(Predicted)
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
PKA: 1.84±0.42(Predicted)
PSA: 38.91000
LogP: 1.52320

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