189333-03-7

Basic information

• Product Name: TERT-BUTYL 2,9-DIAZASPIRO[5.5]UNDECANE-2-CARBOXYLATE
• Synonyms: TERT-BUTYL 2,9-DIAZASPIRO[5.5]UNDECANE-2-CARBOXYLATE;2,9-Diazaspiro[5.5]undecane-2-carboxylic acid, 1,1-dimethylethyl ester;2-Boc-2,9-diazaspiro[5.5]undecane;2,9-Diazaspiro[5.5]undecane-2-carboxylic acid tert-butyl ester;2,9-Diazaspiro[5.5]undecan-2-carboxylic acid tert-butyl ester
• CAS NO: 189333-03-7
• Molecular Formula: C₁₄H₂₆N₂O₂
• Molecular Weight: 254.371
• Mol File: 189333-03-7.mol

Chemical Properties

• Boiling Point: 354℃
• Flash Point: 168℃
• Appearance: /
• Density: 1.05
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.513
• Storage Temp.: 2-8°C(protect from light)
• PKA: 10.97±0.20(Predicted)
• CAS DataBase Reference: TERT-BUTYL 2,9-DIAZASPIRO[5.5]UNDECANE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 2,9-DIAZASPIRO[5.5]UNDECANE-2-CARBOXYLATE(189333-03-7)
• EPA Substance Registry System: TERT-BUTYL 2,9-DIAZASPIRO[5.5]UNDECANE-2-CARBOXYLATE(189333-03-7)

Safety Data

• Hazardous Substances Data: 189333-03-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
TERT-BUTYL 2,9-DIAZASPIRO[5.5]UNDECANE-2-CARBOXYLATE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical sector, TERT-BUTYL 2,9-DIAZASPIRO[5.5]UNDECANE-2-CARBOXYLATE is employed as an intermediate in the production of agrochemicals, aiding in the creation of compounds that can enhance crop protection and yield.
Used in Organic Synthesis:
TERT-BUTYL 2,9-DIAZASPIRO[5.5]UNDECANE-2-CARBOXYLATE is utilized as a versatile building block in organic synthesis, enabling the formation of a wide array of organic compounds for various applications across different industries.

InChI:InChI=1/C14H26N2O2/c1-13(2,3)18-12(17)16-10-4-5-14(11-16)6-8-15-9-7-14/h15H,4-11H2,1-3H3

Upstream product

• 1159982-59-8 tert-butyl 9-benzyl-2,9-diazaspiro[5.5]undecane-2-carboxylate 
• 1198393-02-0 9-benzyl-2,9-diazaspiro[5.5]undecane 

Downstream Products

• 1095707-96-2 9-[3-(2-Methylpyrid-4-yl)-2-phenylimidazo[1,2-b]pyridazin-6-yl]-2,9-diazaspiro[5.5]undecane 
• 1304723-81-6 C₃₁H₄₆N₆O₄S 
• 1350918-44-3 tert-butyl 9-(2-fluoro-6-nitrophenyl)-2,9-diazaspiro[5.5]undecane-2-carboxylate 
• 1350918-45-4 tert-butyl 9-(2-amino-6-fluorophenyl)-2,9-diazaspiro[5.5]undecane-2-carboxylate 
• 1350918-46-5 tert-butyl 9-(2-fluoro-6-(4-(2-methylpyridin-4-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-2-carboxamido)phenyl)-2,9-diazaspiro[5.5]undecane-2-carboxylate 
• 1350916-86-7 N-[2-(2,9-diazaspiro[5.5]undec-9-yl)-3-fluorophenyl]-4-(2-methyl-4-pyridinyl)-1H-imidazole-2-carboxamide 
• 1257881-80-3 2-(3-(4-chlorophenoxy)benzyl)-N-(pyridin-3-yl)-2,9-diazaspiro[5.5]undecane-9-carboxamide 

Relevant articles and documents

Spirocyclic derivatives

The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease, disorder or condition ameliorated by inhibition of a dopamine transporter); and methods of treating patients with such compounds; wherein R1, R2, R3, R4, R5, R6, R9, R10, Q, X, Y, Z, A, L, B, m, n and p are as defined herein.

Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation

This invention relates to certain spirocyclic compounds substituted with both basic and acidic functionality, as shown by formula (I): wherein Q, L, Ai, Bj, R0, R3, R10, m, n, p and q are as defined in the disclosure, which are useful in inhibiting of platelet aggregation.