189683-85-0 Usage
Uses
Used in Pharmaceutical Research:
(R)-3-Methoxymethoxy-mandelonitrile is used as a key intermediate in the synthesis of various pharmaceuticals for its potential biological activity. Its unique structure allows for the development of new drugs with specific therapeutic properties.
Used in Organic Synthesis:
In the field of organic synthesis, (R)-3-Methoxymethoxy-mandelonitrile serves as a versatile building block for creating a wide range of chemical compounds. Its reactivity enables the formation of diverse molecular structures, which can be utilized in various applications.
Used in Anti-Tumor and Anti-Cancer Applications:
(R)-3-Methoxymethoxy-mandelonitrile is studied for its potential as an anti-tumor and anti-cancer agent. Its ability to interact with biological targets makes it a promising candidate for the development of new cancer treatments.
Used in Enzyme Inhibition:
(R)-3-METHOXYMETHOXY-MANDELONITRILE has also been investigated for its ability to inhibit certain enzymes, which can be beneficial in the treatment of various diseases and conditions. By targeting specific enzymes, (R)-3-Methoxymethoxy-mandelonitrile may contribute to the development of novel therapeutic agents.
Used in Specialty Chemicals Production:
(R)-3-Methoxymethoxy-mandelonitrile may have applications in the production of various specialty chemicals, where its unique properties can be harnessed to create high-value products for different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 189683-85-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,6,8 and 3 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 189683-85:
(8*1)+(7*8)+(6*9)+(5*6)+(4*8)+(3*3)+(2*8)+(1*5)=210
210 % 10 = 0
So 189683-85-0 is a valid CAS Registry Number.
189683-85-0Relevant articles and documents
Synthesis of the Adrenergic Bronchodilators (R)-Terbutalinel and (R)-Salbutamol from (R)-Cyanohydrins
Effenberger, Franz,Jaeger, Juergen
, p. 3867 - 3873 (2007/10/03)
Stereoselective syntheses of (R)-terbutaline and (R)-salbutamol acetal, which are important bronchodilators, starting from O-protected (R)-cyanohydrins are described. (R)-Terbutaline hydrochloride (R)-9·HCl is obtained in an overall yield of 44% with >98% ee from the O-bisallyl-protected cyanohydrin (R)-4k via a Ritter N-tertiary butylation to the amide (R)-6a, hydrogenation to the amino alcohol (R)-7a, and deprotection of the hydroxyl functions. (R)-Salbutamol acetals (R)-7b,c can be obtained from the corresponding O-protected (R)-cyanohydrins either via the route described for (R)-terbutaline or via selective hydrogenation of the protected cyanohydrin (R)-11 to the imino derivative, transimination with tert-butylamine, followed by hydrogenation with NaBH4 to give the 2-amino alcohol derivative (R)-12. Desilylation of (A)-12 to (R)-7c is performed with LiAlH4. Hydrolytic cleavage of the acetals (A)-7b and c to (R)-salbutamol was not yet possible without racemization.
