190184-82-8

Basic information

• Product Name: Mono(4-pentenyl)phthalate
• Synonyms: Mono(4-pentenyl)phthalate;1,2-Benzenedicarboxylic Acid Mono-4-pentenyl Ester;1,2-Benzenedicarboxylic Acid, 1-(4-Penten-1-yl) Ester
• CAS NO: 190184-82-8
• Molecular Formula: C₁₃H₁₄O₄
• Molecular Weight: 234.24786
• Product Categories: Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 190184-82-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Mono(4-pentenyl)phthalate(CAS DataBase Reference)
• NIST Chemistry Reference: Mono(4-pentenyl)phthalate(190184-82-8)
• EPA Substance Registry System: Mono(4-pentenyl)phthalate(190184-82-8)

Safety Data

• Hazardous Substances Data: 190184-82-8(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
Mono(4-pentenyl)phthalate is used as a key intermediate in the chemical synthesis of macrocyclic lactones. These macrocyclic lactones are important compounds in the pharmaceutical and chemical industries due to their diverse range of biological activities and potential applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Mono(4-pentenyl)phthalate is used as a building block for the synthesis of various drug molecules. Its unique structural features allow for the creation of novel compounds with potential therapeutic properties, contributing to the development of new medications for various diseases and conditions.
Used in Chemical Research:
Mono(4-pentenyl)phthalate is also utilized in chemical research as a model compound for studying the properties and reactivity of mono-substituted phthalate derivatives. This helps researchers gain a deeper understanding of the structure-activity relationships in this class of compounds and facilitates the design of new molecules with desired properties.

Upstream product

• 85-44-9 phthalic anhydride 
• 821-09-0 n-Pent-4-enyl alcohol 

Downstream Products

• 394658-03-8 phthalic acid 1-hex-5-enyl ester 2-pent-4-enyl ester 
• 394658-02-7 phthalic acid 1-but-3-enyl ester 2-pent-4-enyl ester 
• 394658-04-9 phthalic acid 1-(1-hexyl-but-3-enyl) ester 2-pent-4-enyl ester 
• 394658-05-0 Phthalic acid 1-((R)-1-but-3-enyl-heptyl) ester 2-pent-4-enyl ester 
• 394657-83-1 phthalic acid 1-allyl ester 2-pent-4-enyl ester 
• 190185-33-2 2-Diazo-3-oxo-3-(pent-4-enylcarboxy)phenylpropansaeure-(-)menthylester 
• 190185-27-4 3-Oxo-3-(pent-4-enylcarboxy)phenylpropansaeure(-)menthylester 
• 190185-22-9 2-(Pent-4-enylcarboxy)benzoylmalonsaeure-tert-butylmethylester 
• 190185-31-0 2-Diazo-3-oxo-3-(pent-4-enylcarboxy)phenylpropansaeureethylester 
• 190185-29-6 2-Diazo-3-oxo-3-(pent-4-enylcarboxy)phenylpropansaeuremethylester 
• 190185-25-2 3-Oxo-3-(pent-4-enylcarboxy)phenylpropansaeureethylester 
• 190185-24-1 3-Oxo-3-(pent-4-enylcarboxy)phenylpropansaeuremethylester 
• 146765-81-3 2-Diazoacetylbenzoesaeurepent-4-enylester 

Relevant articles and documents

Efficient phthalate-tethered ring-closing metathesis as a cross-coupling reaction

An efficient method for cross-coupling using phthalate-tethered ring-closing metathesis was developed. Based on this method, the stereocontrolled syntheses of both (R,R)- and (S,R)-1-methoxypentadecane-2,9-diol (17, 20) were achieved from (R)-1-undecen-5-ol (4e) and (R)-1-methoxy-5-hexen-2-ol (13).

Pyryliumolates. III. Synthesis of Annulated Benzotropolones

Dirhodiumtetraacetate catalyzed nitrogen extrusion from diazocarbonyl compounds (2a-f, 19c, 23d-f, 25b) yields benzopyryliumolates (3), which were trapped intramolecularly in situ to give tetracyclic adducts (4a, 5a-d, 20, 24a-c, 26). Starting with 5a and 5d annulated benzotropolones (12a, d) are accessible.

Pyryliumolates. 1. A simple access to anellated benzotropolones

The synthesis of benzotropolones 4a,b utilizing an intramolecular 1,3-dipolar cycloaddition reaction with benzopyryliumolates (2a,b; generated in situ) is reported.