19022-51-6

Basic information

• Product Name: ophiobolin C
• Synonyms: ophiobolin C;3-Hydroxy-5-oxoophiobola-7,19-dien-25-al;Zizanin A
• CAS NO: 19022-51-6
• Molecular Formula: C25H38O3
• Molecular Weight: 386.572
• Mol File: 19022-51-6.mol

Chemical Properties

• Boiling Point: 512.4°Cat760mmHg
• Flash Point: 277.8°C
• Appearance: /
• Density: 1.064g/cm³
• Vapor Pressure: 1.21E-12mmHg at 25°C
• Refractive Index: 1.544
• CAS DataBase Reference: ophiobolin C(CAS DataBase Reference)
• NIST Chemistry Reference: ophiobolin C(19022-51-6)
• EPA Substance Registry System: ophiobolin C(19022-51-6)

Safety Data

• Hazardous Substances Data: 19022-51-6(Hazardous Substances Data)

Usage

Uses

Used in Antiviral Applications:
Ophiobolin C is used as an inhibitor of human CCR5 binding to HIV-1 gp120 for its potential role in treating HIV-1 infection. By blocking the binding of the virus to human cells, it may offer a new mode of action for antiviral therapies.
Used in Cancer Treatment:
Ophiobolin C is used as a cytotoxic agent against chronic lymphocytic leukemia cells, with a reported LC50 of 8 nM, indicating its potential in cancer treatment and research.

InChI:InChI=1/C25H38O3/c1-16(2)7-6-8-17(3)19-11-12-24(4)13-21-23(22(27)14-25(21,5)28)18(15-26)9-10-20(19)24/h7,9,15,17,19-21,23,28H,6,8,10-14H2,1-5H3/b18-9-/t17?,19-,20+,21+,23-,24-,25+/m1/s1

Upstream product

• 6589-10-2 (E)-(1R,3R,3aS,6aS,7R,9aR,10aS)-7-((S)-1,5-Dimethyl-hex-4-enyl)-4-hydroxymethyl-1,9a-dimethyl-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-dicyclopenta[a,d]cyclooctene-1,3-diol 
• 119594-14-8 2,2-Dimethyl-propionic acid (S)-4-{(1R,2S,3S)-3-hydroxymethyl-3-methyl-2-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-cyclopentyl}-pentyl ester 
• 119594-29-5 2,2-Dimethyl-propionic acid (S)-4-{(1R,2S,3S)-3-formyl-3-methyl-2-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-cyclopentyl}-pentyl ester 
• 119594-27-3 (S)-4-{(1R,2S,3S)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-2-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-cyclopentyl}-pentan-1-ol 
• 119619-00-0 {(1S,2S,3R)-3-((S)-4-Benzyloxy-1-methyl-butyl)-1-methyl-2-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-cyclopentylmethoxy}-tert-butyl-diphenyl-silane 
• 119594-28-4 2,2-Dimethyl-propionic acid (S)-4-{(1R,2S,3S)-3-(tert-butyl-diphenyl-silanyloxymethyl)-3-methyl-2-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-cyclopentyl}-pentyl ester 
• 119594-26-2 {(1S,4S,5S)-4-((S)-4-Benzyloxy-1-methyl-butyl)-1-methyl-5-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-cyclopent-2-enylmethoxy}-tert-butyl-diphenyl-silane 
• 119594-24-0 (S)-5-Benzyloxy-2-{(1S,4S,5S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-4-methyl-5-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-cyclopent-2-enyl}-pentan-1-ol 
• 119594-16-0 2,2-Dimethyl-propionic acid (S)-4-[(E)-(3R,3aS,6aR,7R,10aS)-7-(tert-butyl-diphenyl-silanyloxy)-5-hydroxy-10a-methyl-6-methylene-9-oxo-1,2,3,3a,4,5,6,6a,7,8,9,10a-dodecahydro-dicyclopenta[a,d]cycloocten-3-yl]-pentyl ester 
• 119594-32-0 2,2-Dimethyl-propionic acid (S)-4-[(1R,2S,3S)-3-[(2R,3R)-3-(tert-butyl-diphenyl-silanyloxy)-2-(1-iodo-vinyl)-5-oxo-cyclopent-(E)-ylidenemethyl]-2-(2-hydroxy-ethyl)-3-methyl-cyclopentyl]-pentyl ester 
• 119594-35-3 (S)-4-[(E)-(3R,3aS,6aS,7R,9R,9aS,10aR)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-7-(tert-butyl-diphenyl-silanyloxy)-9-hydroxy-9,10a-dimethyl-1,2,3,3a,4,6a,7,8,9,9a,10,10a-dodecahydro-dicyclopenta[a,d]cycloocten-3-yl]-pentanal 
• 119619-02-2 (E)-(1R,3R,3aS,6aS,7R,9aR,10aS)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-3-(tert-butyl-diphenyl-silanyloxy)-7-((S)-1,5-dimethyl-hex-4-enyl)-1,9a-dimethyl-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-dicyclopenta[a,d]cycloocten-1-ol 
• 119618-99-4 2,2-Dimethyl-propionic acid (S)-4-[(1R,2S,3S)-3-[(2R,3R)-3-(tert-butyl-diphenyl-silanyloxy)-2-(1-iodo-vinyl)-5-oxo-cyclopent-(E)-ylidenemethyl]-3-methyl-2-(2-oxo-ethyl)-cyclopentyl]-pentyl ester 
• 119619-01-1 C₄₂H₅₈O₆Si