19036-27-2

Basic information

• Product Name: 1,4-BIS(BROMMETHYL)-2,5-DICHLOROBENZENE
• Synonyms: 1,4-BIS(BROMMETHYL)-2,5-DICHLOROBENZENE;1,4-Bis(bromomethyl)-2,5-dichlorobenzene;ALPHA,ALPHA'-DIBROMO-2,5-DICHLORO-P-XYLENE
• CAS NO: 19036-27-2
• Molecular Formula: C₈H₆Br₂Cl₂
• Molecular Weight: 332.85
• Mol File: 19036-27-2.mol

Chemical Properties

• Boiling Point: 333.7 °C at 760 mmHg
• Flash Point: 175.3 °C
• Appearance: /
• Density: 1.931 g/cm³
• Vapor Pressure: 0.000261mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: 1,4-BIS(BROMMETHYL)-2,5-DICHLOROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-BIS(BROMMETHYL)-2,5-DICHLOROBENZENE(19036-27-2)
• EPA Substance Registry System: 1,4-BIS(BROMMETHYL)-2,5-DICHLOROBENZENE(19036-27-2)

Safety Data

• Hazardous Substances Data: 19036-27-2(Hazardous Substances Data)

Usage

Uses

Used in Pesticide Industry:
1,4-Bis(bromomethyl)-2,5-dichlorobenzene is used as an active ingredient in pesticides for its ability to control and eliminate pests. Its high toxicity makes it effective in combating various types of pests, thereby protecting crops and ensuring agricultural productivity.
Used as a Chemical Intermediate:
In the chemical industry, 1,4-Bis(bromomethyl)-2,5-dichlorobenzene serves as a crucial intermediate in the synthesis of other organic compounds. Its unique structure and reactivity make it a valuable building block for the development of new chemical products with diverse applications.

InChI:InChI=1/C8H6Br2Cl2/c9-3-5-1-7(11)6(4-10)2-8(5)12/h1-2H,3-4H2

Upstream product

• 111-88-6 Octanethiol 
• 1124-05-6 1,4-dichloro-2,5-dimethylbenzene 

Downstream Products

• 35335-13-8 [2,5-Dichloro-4-(diethoxy-phosphorylmethyl)-benzyl]-phosphonic acid diethyl ester 
• 50987-90-1 1,4-bis(chloromethyl)-2,5-dichlorobenzene 
• 56403-43-1 1,4-Bis-(cyanomethyl)-2,5-dichlorbenzol 
• 807630-01-9 1-chloromethyl-4-(n-octylsulfinyl)methyl-2,5-dichlorobenzene 
• 35335-14-9 trans,trans-2,5-Bis(2-iodstyryl)-1,4-dichlorbenzol 

Relevant articles and documents

A new protocol for the synthesis of 4,7,12,15-tetrachloro[2.2]paracyclophane

We report a green and convenient protocol to prepare 4,7,12,15-tetrachloro[2.2]paracyclophane, the precursor of parylene D, from 2,5-dichloro-p-xylene. In the first bromination step, with H2O2-HBr as a bromide source, this procedure becomes organic-waste-free and organic-solvent-free and can appropriately replace the existing bromination methods. The Winberg elimination-dimerization step, using aqueous sodium hydroxide solution instead of silver oxide for anion exchange, results in a significant improvement in product yield. Furthermore, four substituted [2.2]paracyclophanes were also prepared in this convenient way.

THERAPEUTIC INHIBITORY COMPOUNDS

The invention provides compounds of Formula I and Formula II: A-B-C-D-E-F-G-J (I) C-D-E-F-G-J (II) wherein A, B, C, D, E, F, G, and J have any of the values defined in the specification, and salts thereof. The compounds are useful for inhibiting plasma kallikrein, and for treating a disease or condition in an animal where inhibition of plasma kallikrein is indicated.

Synthesis and complete NMR spectral assignment of thiophene-substituted sulfinyl monomers

This paper describes the synthesis of thiophene-substituted sulfinyl monomers. It comprises a four-step reaction by which the thiophene unit is built in via Suzuki coupling. These monomers could be used as building blocks for the preparation of conducting

Scope and Limitations of a New Highly Selective Synthesis of Unsymmetrical Monomers for the Synthesis of Precursors toward Poly(arylenevinylene)s

In our laboratory a precursor route to poly(p-phenylenevinylene) derivatives is developed in which unsymmetrically substituted p-xylene derivatives, possessing a benzylic sulfinylalkyl group, are used as monomers. Because of this unsymmetry, we were forced to investigate thoroughly the synthesis of these sulfoxides, as we start from symmetric and readily accessible molecules, namely, bis(halomethyl)-p-xylene derivatives. In a former publication, a new extremely effective route for the production of these unsymmetrically substituted sulfinyl monomers was presented. This paper expands upon these previously reported results. To examine the scope and limitations of this elegant route, this new method was applied to the synthesis of various derivatives not included in the initial work.

Thia-and/or selenafulvalenyl group-containing compound

A thia- and/or selenafulvalenyl group-containing compound of the formula (I), STR1 wherein each of X1, X2, X3, X4, X'1, X'2, X'3 and X'4 is independently S or Se, Y is an electron donating or electron accepting group having a size which is not so large as to prevent molecular overlapping, m is an integer of 0 to 4, each of Z1, Z2, Z'1 and Z'2 is independently a hydrogen atom, Cn H2n+1 in which n is an integer of 1 to 5, or alternatively, a combination of Z1 with Z2 and Z'1 with Z'2 is Cn H2n in which n is an integer of 1 to 5, or X(Cn H2n)n', X in which X is S or Se and n' is an integer of 1 to 3, and each of R1, R2, R3, R'1, R'2 and R'3 is independently a hydrogen atom or Cn H2n+1 in which n is an integer of 1 to 5. The compound has an electron donating nature and can be used to make electrically conductive complexes. The compound has an excellent thermal stability.