190436-96-5Relevant articles and documents
BENZOXAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION
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Page/Page column 42; 51, (2008/06/13)
There is provided the use of a compound of formula (I),wherein Y, W1 to W4, Z1 to Z4 and R have meanings given in the description, and pharmaceutically-acceptable salts thereof, for the manufacture of a medicame
Synthesis and SAR of 2-arylbenzoxazoles, benzothiazoles and benzimidazoles as inhibitors of lysophosphatidic acid acyltransferase-β
Gong, Baoqing,Hong, Feng,Kohm, Cory,Bonham, Lynn,Klein, Peter
, p. 1455 - 1459 (2007/10/03)
2-Arylbenzoxazoles, benzothiazoles and benzimidazoles were identified as new classes of potent, isoform specific inhibitors of lysophosphatidic acid acyltransferase-β (LPAAT-β). Effects of selected inhibitors on proliferation of tumor cells in vitro were investigated.
Benzoxazole LPAAT-B inhibitors and uses thereof
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, (2008/06/13)
The invention relates to benzoxazoles and the use thereof to inhibit lysophosphatidic acid acyltransferase β (LPAAT-β) activity. The invention further relates to methods of treating cancer using said benzoxazoles. The invention also relates to methods for screening for LPAAT-β activity.