190774-14-2

Basic information

• Product Name: N-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)acetamide
• Synonyms: benzeneacetamide, N-(3,5-dimethoxyphenyl)-4-methoxy-
• CAS NO: 190774-14-2
• Molecular Formula: C₁₇H₁₉NO₄
• Molecular Weight: 301.3371
• Mol File: 190774-14-2.mol

Chemical Properties

• Boiling Point: 514.9°C at 760 mmHg
• Flash Point: 265.2°C
• Density: 1.18g/cm³
• Vapor Pressure: 1.03E-10mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: N-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)acetamide(190774-14-2)
• EPA Substance Registry System: N-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)acetamide(190774-14-2)

Safety Data

• Hazardous Substances Data: 190774-14-2(Hazardous Substances Data)

Upstream product

• 10272-07-8 3.5-dimethoxyaniline 
• 4693-91-8 4-methoxyphenyl-acetic chloride 

Downstream Products

• 256424-07-4 1-[2-(1H-1,2,3,4-tetrazol-5-yl)ethyl]-5,7-dimethoxy-3-(4-methoxyphenyl)-1,2-dihydro-2-quinolinone 
• 256424-00-7 3-[5,7-Dimethoxy-3-(4-methoxyphenyl)-2-oxo-1,2-dihydro-1-quinolinyl]propanoic Acid 
• 256423-91-3 5,7-Dihydroxy-3-(4-hydroxyphenyl)-1-methyl-1,2-dihydro-2-quinolinone 
• 256423-87-7 5,7-Dimethoxy-3-(4-methoxyphenyl)-1-methyl-1,2-dihydro-2-quinolinone 
• 256423-92-4 5,7-Dimethoxy-3-(4-methoxyphenyl)-1-methyl-1,2-dihydro-2-quinolinethione 
• 256423-89-9 3-(4-hydroxy-phenyl)-5,7-dimethoxy-1-methyl-1H-quinolin-2-one 

Relevant articles and documents

Pharmaceutical compositions comprising 2-quinolones

The invention concerns a pharmaceutical composition having an activity on the proliferation of clonogenic cells in tumours and comprising an efficient amount of a compound selected among the compounds of formulae (I) and (Ia) wherein: X, R1, R

3-Aryl-2-quinolone derivatives: Synthesis and characterization of in vitro and in vivo antitumor effects with emphasis on a new therapeutical target connected with cell migration

Among 25 3-aryl-2-quinolone derivatives synthesized, the antitumor activity of some of them was characterized both in vitro and in vivo. In this series, no compound appeared to be cytotoxic in vitro, as was known by the colorimetric MTT assay carried out

Synthesis of 3-(4-methoxyphenyl)-5,7-dimethoxy-(1H)-quinolin-2- or 4-ones and derivatives

Condensation of ethyl 2-(4-methoxyphenyl)-3-hydroxyacrylate with 3,5-dimethoxyaniline afforded, depending on experimental conditions, either 3-(4-methoxyphenyl)-5,7-dimethoxy-(1H)-quinolin-2-one or 3-(4-methoxyphenyl)-5,7-dimethoxy-(1H)-quinolin-4-one. Whereas chlorination with phosphorous oxychloride led to the corresponding 2- and 4- chloroquinolines derivatives, 2-chloro-3-(4-methoxyphenyl)-5,7-dimethoxyquinoline was also obtained by using the Meth Cohn method's.