- Synthesis of Thiourea and Sulfonylurea Derivatives of Chalcones and Flavones and their Biological Evaluation
-
Chalcone and flavone derivatives based on thiourea and sulfonylurea (6, 7a and 7b, 13a and 13b) were synthesized and confirmed by spectral data. All the target compounds were evaluated for in vivo antihyperglycemic activity in sucrose loaded model (SLM) a
- Pratap, Ram,Satyanarayana, Mavurapu,Shukla, Poonam,Srivastava, Arvind K,Tiwari, Priti,Tripathi, Brajendra K
-
p. 341 - 345
(2021/11/22)
-
- READ-THROUGH INDUCER AND PHARMACEUTICAL USE THEREOF
-
PROBLEM TO BE SOLVED: To provide a novel read-through inducer. SOLUTION: The present invention relates to a compound represented by the general formula (I) [each symbol in the formula is as described in the specification] or a pharmaceutically acceptable
- -
-
Paragraph 0447; 0452-0454
(2020/08/04)
-
- Nickel catalysed carbonylative Sonogashira reaction for the synthesis of diarylalkynones and 2-substituted flavones
-
The nickel catalyzed, palladium/phosphine free carbonylative Sonogashira reaction of terminal alkynes with substituted aryl and heteroaryl iodides is described. This protocol provides mild and robust conditions to synthesize a variety of substituted aryl α,β-alkynyl ketones and flavones in good to excellent isolated yields. This methodology tolerates several functional groups such as electron donating (methyl, isopropyl, tert-butyl, methoxy) as well as electron withdrawing (trifluoromethyl, nitro, esters, nitrile) groups on the terminal alkynes and iodides.
- Charugandla, Renuka,Vangala, Markandeya Sarma,Chidara, Sridhar,Korupolu, Raghu Babu
-
supporting information
p. 3283 - 3287
(2018/07/25)
-
- Synthesis and structure elucidation of five series of aminoflavones using 1D and 2D NMR spectroscopy
-
Twenty-six new aminoflavones have been synthesised by two different methods and the structure elucidation was accomplished using extensive 1D ( 1H, 13C) and 2D NMR spectroscopic studies (COSY, HSQC and HMBC experiments). Copyright
- Barros, Ana I. R. N. A.,Silva, Artur M. S.
-
p. 1122 - 1127
(2008/02/03)
-
- Syntheses of some New Heterocycles from 4'-Aminochromones. Part I
-
Syntheses of some new pyrazoles from hitherto unknown 4'-aminochromones have been described.Their structures have been confirmed on the basis of elemental analysis and spectral data.
- Mazumdar, A. K. D.,Das, S. C.,Karmakar, P. K.,Saha, N. K.,Banerji, K. D.
-
p. 761 - 764
(2007/10/02)
-
- Synthesis and Biological Activity of some 2-Aryl-4H-1-benzopyran-4-ones
-
A new three-step synthesis of 2-(4-aminophenyl)-4H-1-benzopyran-4-one (4) is reported. 2--4H-1-benzopyran-4-one (6a-c) and 2--4H-1-benzopyran-4-one (7a-c) have been synthesised f
- Coutinho, Dionysia L. M.,Fernandes, Peter S.
-
p. 265 - 267
(2007/10/02)
-
- Synthesis and Protein-Tyrosine Kinase Inhibitory Activities of Flavanoid Analogues
-
Treatment of o-hydroxyacetophenones 2a-e with excess lithium bis(trimethylsilyl)amide followed by dialkyl carbonates gave 3-(2-hydroxyaryl)-3-oxopropanoates 3a-e.The latter substances were transformed through the reaction of their magnesium chelates with
- Cushman, Mark,Nagarathnam, Dhanapalan,Burg, Debra L.,Geahlen, Robert L.
-
p. 798 - 806
(2007/10/02)
-
- Synthesis of Some New Heterocycles from 4'-Amino Flavone
-
A convenient synthesis, with good yields, for 4'-amino flavone (VI) using sodium dithionite as a reducing agent is presented.A few disubstituted thioureas (VIIa, b, c) have been prepared from VI. 4'-Hydrazino-flavone (IX) has been synthesised for the firs
- Fernandes, Peter S.,Coutinho, Louis
-
p. 864 - 866
(2007/10/02)
-