- Syntheses of racemic and scalemic cis-chrysanthemic acid from β,γ-unsaturated cyclohexanol
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2,2,5,5-Tetramethylcyclohexane-1,3-dione is a valuable starting-material precursor of cis-chrysanthemic acid. The (1S)-stereoisomer is a precursor of pyrethrin I, the most active natural insecticide from Chrysanthemum cinerariifolium, whereas the (1R)-stereoisomer is efficiently transformed to deltamethrin, the most active commercially available pyrethroid insecticide. Several intermediates have been identified and used with variable success for that purpose.
- Krief, Alain,Jeanmart, Stéphane,Gondal, Humaira Y.,Kremer, Adrian
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p. 2123 - 2167
(2013/02/23)
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