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191729-44-9

Tenacissoside I is a triterpenoid saponin derived from the roots of Pulsatilla chinensis, a traditional Chinese medicinal herb. It exhibits a range of pharmacological properties, such as anti-inflammatory, anti-cancer, and antioxidant activities. Tenacissoside I has demonstrated the ability to inhibit the growth and proliferation of various cancer cells, while also enhancing the body's immune response. Furthermore, Tenacissoside I has been reported to have protective effects on the liver and exhibit analgesic properties. Its promising biological activities have led to ongoing research for potential therapeutic applications in the treatment of various diseases.

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  • 191729-44-9 Structure

  • Basic information

    1. Product Name: Tenacissoside I
    2. Synonyms: (3beta,5alpha,11alpha,12beta,14beta,17alpha)-12-(Acetyloxy)-11-(benzoyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-beta-D-allopyranosyl)-3-O-methyl-beta-D-arabino-hexopyranosyl]oxy]-8,14-epoxypregnan-20-one;Tenacissimoside B;Teacissoside I;Tenacissoside I
    3. CAS NO:191729-44-9
    4. Molecular Formula: C44H62O14
    5. Molecular Weight: 814.95500
    6. EINECS: N/A
    7. Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
    8. Mol File: 191729-44-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 850.8±65.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.30
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 12.89±0.70(Predicted)
    10. CAS DataBase Reference: Tenacissoside I(CAS DataBase Reference)
    11. NIST Chemistry Reference: Tenacissoside I(191729-44-9)
    12. EPA Substance Registry System: Tenacissoside I(191729-44-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 191729-44-9(Hazardous Substances Data)

191729-44-9 Usage

Uses

Used in Pharmaceutical Industry:
Tenacissoside I is used as an anti-inflammatory agent for its ability to reduce inflammation and alleviate associated symptoms.
Used in Oncology:
Tenacissoside I is used as an anti-cancer agent for its potential to inhibit the growth and proliferation of various cancer cells, making it a candidate for cancer treatment.
Used in Immunotherapy:
Tenacissoside I is used as an immune system enhancer for its capacity to boost the body's immune response, which can be beneficial in fighting infections and diseases.
Used in Hepatoprotective Applications:
Tenacissoside I is used as a liver protectant for its reported protective effects on the liver, which can be useful in treating liver diseases and conditions.
Used in Pain Management:
Tenacissoside I is used as an analgesic for its pain-relieving properties, offering potential relief for individuals suffering from various types of pain.

Check Digit Verification of cas no

The CAS Registry Mumber 191729-44-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,7,2 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 191729-44:
(8*1)+(7*9)+(6*1)+(5*7)+(4*2)+(3*9)+(2*4)+(1*4)=159
159 % 10 = 9
So 191729-44-9 is a valid CAS Registry Number.

191729-44-9Upstream product

191729-44-9Downstream Products

191729-44-9Relevant articles and documents

Three new polyoxypregnane glycosides from Marsdenia tenacissima

Deng, Jun,Liao, Zhixin,Chen, Daofeng

, p. 2675 - 2682 (2005)

Three new polyoxypregnane glycosides, marsdenosides I-K (1-3), were isolated from the stem of Marsdenia tenacissima. The structures were elucidated on the basis of in-depth spectroscopic analyses, and by means of chemical evidence. Marsdenoside I (=(3β,5α

Polyoxypregnane steroids from the stems of marsdenia tenacissima

Yao, Sheng,To, Kenneth Kin-Wah,Wang, Ya-Zhou,Yin, Chun,Tang, Chunping,Chai, Stella,Ke, Chang-Qiang,Lin, Ge,Ye, Yang

, p. 2044 - 2053 (2014/12/11)

A new polyoxypregnane aglycone, tenacigenin D (1), and seven new C21 steroid glycosides, tenacissimosides D-J (2-8), were isolated from the stems of Marsdenia tenacissima. Their structures were determined by interpretation of their 1D and 2D NMR and other spectroscopic data, as well as by comparison with published values for related known compounds. Compound 1 was found to circumvent P-glycoprotein (P-gp)-mediated multidrug resistance through an inhibitory effect on P-gp with a similar potency to verapamil. In addition, compound 1 potentiated the activity of erlotinib and gefitinib in epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI)-resistant non-small-cell lung cancer cells.

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