19215-52-2Relevant articles and documents
Dual Functional Half-Sandwich Ru(II) Complexes: Lysosome-Targeting Probes and Anticancer Agents
Liu, Zhe,Li, JuanJuan,Kong, Deliang,Tian, Meng,Zhao, Yao,Xu, Zhishan,Gao, Wenyuan,Zhou, Yumin
, p. 287 - 294 (2019/01/10)
It is known that the proposed biologically active form of ruthenium is its oxidation state II other than oxidation state III, and ruthenium complexes offer the potential of a novel mechanism of action, reduced toxicity. Herein, three half-sandwich Ru
The formation of dinuclear trichloro-bridged and mononuclear ruthenium complexes from the reactions of dichlorotris(p-tolylphosphine)ruthenium(II) with diazabutadiene ligands
Tay, Meng Guan,Chia, Ying Ying,Kuan, Suzie Hui Chin,Phan, Tze Pei
, (2019/01/04)
Ru(II) complexes with diazabutadiene (R-DAB) ligands have been prepared. The reaction of RuCl3·nH2O with P(p-tolyl)3 gave a [RuCl2{P(p-tolyl)3}] precursor, whose reactions with R-DAB in toluene gave d
Synthesis of exo-Imidazolidin-2-one Dienes, Their Isomerization, and Selectivity in Diels-Alder Cycloadditions
Espinoza-Hicks, Carlos,Montoya, Pablo,Bautista, Rafael,Jiménez-Vázquez, Hugo A.,Rodríguez-Valdez, Luz M.,Camacho-Dávila, Alejandro A.,Cossío, Fernando P.,Delgado, Francisco,Tamariz, Joaquín
, p. 5347 - 5364 (2018/05/28)
An efficient and alternative synthesis of exo-imidazolidin-2-one dienes is described. A condensation reaction was carried out with bis-imino derivatives, diacetyl, and triphosgene, affording symmetrically N,N-disubstituted dienes. The use of alkyl methyl
Synthesis, characterization of zinc complexes with neutral α-diimine ligands and application in ring-opening polymerization of σ-caprolactone
Wang, Xiaodan,Liu, Xuehong,Huang, Ju
, p. 773 - 776 (2017/12/08)
A series of neutral α-diimine ligands with diacetyl and acenaphthenequinone skeletons were prepared by the reaction between diacetyl and the corresponding aromatic amine. These ligands reacted with ZnCl2 to generate symmetric α-diimine zinc complexes C1-C
Highly active and cis-1,4 selective polymerization of 1,3-butadiene catalyzed by cobalt(II) complexes bearing α-diimine ligands
Jia, Xiangyu,Liu, Heng,Hu, Yanming,Dai, Quanquan,Bi, Jifu,Bai, Chenxi,Zhang, Xuequan
, p. 1560 - 1569 (2013/10/01)
A series of cobalt(II) complexes bearing α-diimine ligands were synthesized and characterized by elemental and spectroscopic analysis. These complexes had the general formulas [ArN=C(Me)-(Me)C=NAr]CoCl2 (Ar = C6H5, 3a; 4-M
Synthesis of 1,4-diazabutadienes (=N,N′-ethane-1,2- diylidenebis[amines]) by grinding
He, Jingyu,Xin, Hongxing,Yan, Hong,Song, Xiuqing,Zhong, Rugang
experimental part, p. 159 - 162 (2011/03/16)
A simple and convenient method for the synthesis of 1,4-diazabutadienes (=N,N′-ethane-1,2-diylidenebis[amines]) by grinding glyoxal (=ethanedial) or an α-diketone and anilines (=benzenamines) in the presence of TsOH in a mortar with a pestle is described.
Stereoselective synthesis of cis- and trans-4-acyl-β-lactams from vicinal diketones and ketoaldehydes
Wang, Zhixin,Xu, Jiaxi
experimental part, p. 1711 - 1717 (2012/05/19)
4-Acyl-β-lactams are important synthetic intermediates in both pharmaceutical and organic chemistry. Cis- and trans-4-acyl-β-lactams were synthesized stereoselectively from vicinal diketones via the formation of bulky and less bulky diimines as key interm
Selectivities in the reaction of vicinal diimines and acyl chlorides
Wang, Zhixin,Chen, Ning,Xu, Jiaxi
supporting information; experimental part, p. 9690 - 9699 (2012/01/06)
The reaction of vicinal diimines and acyl chlorides in the presence of triethylamine produces 3-imino-β-lactams and/or bis-β-lactams chemo-, regio-, and stereoselectively, which are important intermediates in pharmaceutical and organic synthesis. The selectivities in the reaction have been investigated. The results indicate that all diimines react with various ketenes generated from acyl chlorides in the presence of triethylamine to give rise to cis-4-imino-β-lactams (mono-cis-β-lactams) diastereoselectively due to the electron-withdrawing property of the imino group in the vicinal diimines. Bis-β-lactams were obtained from diimines via the mono-cis-β-lactams as intermediates. Only ketenes with strong electron-donating substituents can react with the mono-cis-β-lactams to yield bis-β-lactams, affording a pair of C2-symmetric cis-bis-β- lactams with symmetric diimines, two or four pairs of diastereomeric bis-β-lactams with ketoaldehyde-derived unsymmetric diimines depending on the steric hindrance of their N-substituents. The current investigation provides very important information for the selective preparation of mono- and bis-β-lactams from vicinal diimines.
Interaction of drug based binuclear mixed-ligand complexes with DNA
Patel, Mohan N.,Chhasatia, Mehulsinh R.,Gandhi, Deepen S.
experimental part, p. 5648 - 5655 (2009/12/06)
Here in we tried to increase an antibacterial activity of ciprofloxacin drug due to formation of mixed-ligand complexes. Synthesized compounds were found to be more potent compare to drugs, ligands and metal salt against selective gram(+ve) and
Solvent effect on the sensitized photooxygenation of cyclic and acyclic α-diimines
Lemp, Else,Zanocco, Antonio L.,Günther, German,Pizarro, Nancy
, p. 10734 - 10746 (2007/10/03)
The reaction of singlet molecular oxygen with a series of cyclic and acyclic α-diimines was studied. Time-resolved methods were used to measure total reaction rate constants and steady-state methods were used to determine chemical reaction rate constants. GC-MS was used to tentatively assign the reaction products. 5,6-Disubstituted cyclic α-diimines are singlet oxygen quenchers, but become more effective in polar solvents. A reaction mechanism involving a perepoxide intermediate or transition state leading to a hydroperoxide seems to be a key reaction path for product formation. A replacement of the phenyl substituent for a methyl substituent opens up an additional reaction involving a perepoxide-like exciplex, which increases singlet oxygen quenching of the cyclic α-diimines. The reactivity of 5,6-disubstituted cyclic α-diimines towards singlet oxygen is highly dependent on steric interactions arising from vicinal phenyl rings and from electronic effects. 1,4-Disubstituted acyclic α-diimines are, by comparison, moderate or poor singlet oxygen quenchers. Total rate constants are scarcely dependent on solvent properties, but instead correlate with the Hildebrand parameter. These results are explained in terms of a mechanism involving a dioxetane-like exciplex that gives rise to a charged intermediate leading to products.