192189-16-5

Basic information

• Product Name: 1-Boc-3-bromo-5-azaindole
• Synonyms: 1-Boc-3-bromo-5-azaindole;tert-butyl 3-bromo-1H-pyrrolo[3,2-c]pyridine-1-carboxylate
• CAS NO: 192189-16-5
• Molecular Formula: C₁₂H₁₃BrN₂O₂
• Molecular Weight: 297.14782
• Mol File: 192189-16-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-Boc-3-bromo-5-azaindole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Boc-3-bromo-5-azaindole(192189-16-5)
• EPA Substance Registry System: 1-Boc-3-bromo-5-azaindole(192189-16-5)

Safety Data

• Hazardous Substances Data: 192189-16-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
1-Boc-3-bromo-5-azaindole is used as a key building block for the synthesis of pharmaceuticals, contributing to the creation of a wide range of organic compounds. Its presence of a Boc protecting group and a bromine atom at a strategic position on the indole ring facilitates various chemical reactions, making it a versatile component in the development of new drugs.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-Boc-3-bromo-5-azaindole is utilized as a valuable tool for the development of novel drugs. Its unique structure and reactivity allow for the preparation of diverse chemical compounds, which can be further modified and optimized for specific therapeutic applications, enhancing the discovery and design of new pharmaceutical agents.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 23612-36-4 3-bromo-1H-pyrrolo[3,2-c]pyridine 
• 271-34-1 5-azaindole 

Downstream Products

• 1334711-78-2 3-(4-chlorophenyl)-1-(oxan-4-yl)-1H-pyrrolo[3,2-c]pyridine 
• 1334711-77-1 3-(4-chlorophenyl)-1-(oxolan-3-yl)-1H-pyrrolo[3,2-c]pyridine 
• 1334711-76-0 tert-butyl 4-[3-(4-chlorophenyl)-1H-pyrrolo[3,2-c]pyridin-1-yl]piperidine-1-carboxylate 
• 1334711-75-9 3-(4-chlorophenyl)-1-(oxolan-3-ylmethyl)-1H-pyrrolo[3,2-c]pyridine 
• 1334712-91-2 3-(4-chlorophenyl)-1H-pyrrolo[3,2-c]pyridine 
• 1334712-90-1 tert-butyl 3-(4-chlorophenyl)-1H-pyrrolo[3,2-c]pyridine-1-carboxylate 
• 192189-29-0 2-(5-azaindol-3-yl)-5,11-dihydro-11-ethyl-5-methyl-6H-dipyrido[3,2-b;2',3'-e][1,4]diazepin-6-one 

Relevant articles and documents

New Enzyme Inhibitor Compounds

Disclosed are compounds which inhibit SSAO enzyme activity. Also disclosed are pharmaceutical compositions comprising these compounds and the use of these compounds in the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases, immune disorders and the inhibition of tumour growth.

NEW ENZYME INHIBITOR COMPOUNDS

Compounds of formula (I) are inhibitors of Semicarbazide-sensitive amine oxidase wherein R1, A, X and R2 are as defined in the claims.

5-AZAINDOLE BISPHOSPHONATES

Novel 5-azaindole bisphosphonate compounds are disclosed, as well as methods of preparing the compounds, pharmaceutical compositions including the compounds, and administration of the compounds in methods of treating abnormal calcium and phosphate metabolism, including bone and joint diseases and other disorders.

Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. 6. 2-Indol-3-yl- and 2-azaindol-3-yl- dipyridodiazepinones

Modification of the non-nucleoside inhibitor of HIV-1 reverse transcriptase nevirapine (Viramune) by incorporation of a 2-indolyl substituent confers activity against several mutant forms of the enzyme.