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TRIMETHYLSILYL ACETYLENECARBOXYLATE is a chemical compound that serves as a versatile precursor in organic synthesis for the preparation of various functionalized molecules. It is a derivative of acetylenecarboxylic acid, characterized by the presence of a trimethylsilyl group attached to the acetylene carbon atom. This modification enhances the molecule's stability and reactivity, making it a valuable component in a range of chemical reactions and applications.

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  • 19232-22-5 Structure
  • Basic information

    1. Product Name: TRIMETHYLSILYL ACETYLENECARBOXYLATE
    2. Synonyms: TRIMETHYLSILYL PROPIOLATE;TRIMETHYLSILYL ACETYLENECARBOXYLATE
    3. CAS NO:19232-22-5
    4. Molecular Formula: C6H10O2Si
    5. Molecular Weight: 142.23
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 19232-22-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 70-75 °C(lit.)
    3. Flash Point: 68 °F
    4. Appearance: /
    5. Density: 0.925 g/mL at 25 °C(lit.)
    6. Refractive Index: n20/D 1.416(lit.)
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: TRIMETHYLSILYL ACETYLENECARBOXYLATE(CAS DataBase Reference)
    10. NIST Chemistry Reference: TRIMETHYLSILYL ACETYLENECARBOXYLATE(19232-22-5)
    11. EPA Substance Registry System: TRIMETHYLSILYL ACETYLENECARBOXYLATE(19232-22-5)
  • Safety Data

    1. Hazard Codes: F,C
    2. Statements: 11-34
    3. Safety Statements: 16-26-33-36/37/39-45
    4. RIDADR: UN 2924 3/PG 2
    5. WGK Germany: 3
    6. RTECS:
    7. F: 10-21
    8. HazardClass: 3.1
    9. PackingGroup: II
    10. Hazardous Substances Data: 19232-22-5(Hazardous Substances Data)

19232-22-5 Usage

Uses

Used in Organic Synthesis:
TRIMETHYLSILYL ACETYLENECARBOXYLATE is used as a precursor for the synthesis of a variety of functionalized molecules, taking advantage of its increased stability and reactivity due to the trimethylsilyl group.
Used in Carbon-Carbon Bond Formation:
In the field of organic chemistry, TRIMETHYLSILYL ACETYLENECARBOXYLATE is utilized as a reagent for the formation of carbon-carbon bonds. It is particularly useful in reactions such as cross-coupling, cycloaddition, and cyclopropanation, where its unique structure facilitates the creation of new molecular frameworks.
Used in Heterocyclic Compound Synthesis:
TRIMETHYLSILYL ACETYLENECARBOXYLATE is employed as a key component in the synthesis of heterocyclic compounds, which are important in various areas of chemistry, including pharmaceuticals and materials science, due to their diverse structures and properties.
Used in Pharmaceutical Industry:
Within the pharmaceutical sector, TRIMETHYLSILYL ACETYLENECARBOXYLATE is used as a building block for the synthesis of pharmaceutical intermediates. Its compatibility with various functional groups makes it suitable for the development of complex molecular structures that can exhibit specific biological activities.
Used in Natural Product Synthesis:
In the synthesis of natural products, TRIMETHYLSILYL ACETYLENECARBOXYLATE is used as a versatile intermediate. Its ability to participate in a wide array of reactions allows for the construction of complex natural product frameworks, facilitating the development of novel compounds with potential biological significance.

Check Digit Verification of cas no

The CAS Registry Mumber 19232-22-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,2,3 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 19232-22:
(7*1)+(6*9)+(5*2)+(4*3)+(3*2)+(2*2)+(1*2)=95
95 % 10 = 5
So 19232-22-5 is a valid CAS Registry Number.

19232-22-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-trimethylsilylprop-2-ynoate

1.2 Other means of identification

Product number -
Other names Trimethyl-propioloyloxysilan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19232-22-5 SDS

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