Resolution of chiral phosphate, phosphonate, and phosphinate esters by an enantioselective enzyme library
An array of 16 enantiomeric pairs of chiral phosphate, phosphonate, and phosphinate esters was used to establish the breadth of the stereoselective discrimination inherent within the bacterial phosphotriesterase and 15 mutant enzymes. For each substrate,
Nowlan, Charity,Li, Yingchun,Hermann, Johannes C.,Evans, Timothy,Carpenter, Joseph,Ghanem, Eman,Shoichet, Brian K.,Raushel, Frank M.
p. 15892 - 15902
(2007/10/03)
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