- Thiadiazole sulfone compound as well as preparation method and application thereof
-
The invention relates to the field of agricultural fungicides and discloses a thiadiazole sulfone compound as well as a preparation method and application thereof. The compound has a structure expressed by a formula (I) which is as shown in the descriptio
- -
-
-
- ZnCl2 catalyzed efficient synthesis of 1,3,4-oxadiazole and 1,3,4-thiadiazole
-
New methods for the synthesis of 1,3,4-oxadiazole and 1,3,4-thiadiazole have been described. No cyclizations took place in the absence of ZnCl 2. 1,3,4-Thiadiazoles are formed in the presence of ZnCl2 alone, whereas oxadiazoles are produced when a base such as Et3N or KOH was used along with ZnCl2. % Yields are optimized.
- Rahman, Md.A.,Karim, Mohammad R.,Arifuzzaman, Md.,Siddiquee, Tasneem A.,Mirza, Aminul H.
-
p. 3267 - 3273
(2014/06/09)
-
- Synthesis and anticonvulsant activity of 5-aryl-1,3,4-thiadiazole derivatives
-
5-Aryl-1,3,4-thiadiazole derivatives were synthesized and tested for anticonvulsant activity using the pentylenetetrazole-induced lethal convulsion test. The results showed that 2-amino derivatives have anticonvulsant activity (LD50 > 500 mg kg-1) and this effect was not mediated through benzodiazepine receptors. The fluoro electron-withdrawing substituent on the phenyl ring did not potentiate the activity of the compounds.
- Foroumadi,Tabatabai,Gitinezhad,Zarrindast,Shafiee
-
-
- CHEMICAL INTERACTIONS BETWEEN TETRACYANOETHYLENE AND S-METHYLDITHIOCARBAZATE AS WELL AS AZOMETHINE DERIVATIVES
-
The charge-transfer (CT) complexes of Shiff bases 2a-e derived from S-methyldithiocarbazate and tetracyanoethylene (TCNE) have been studied spectrophotometrically.S-methyldithiocarbazate 1 reacted with TCNE to yield 3-amino-4,5-dicyano-6-S-methyl-pyridazine 12 and 4,5-diamino-1,8-di-S-methylpyridazinopyridazine 13 via CT-complexes, whereas 2a-e reacted with TCNE to afford 3-aryl-4-amino-5-cyano-6-S-methylpyridazines 22 and 3-aryl-5-S-methyl-1,2,4-thiadiazoles 16. KEYWORDS: Schiff base, biological activity, methyldithiocarbazate, NMR spectra, IR spectra
- Hassan, Alaa A.
-
p. 189 - 196
(2007/10/02)
-
- A novel synthesis of thiadiazole and thiadiazine derivatives via charge-transfer complexation
-
S-Methyl dithiocarbazate 2 reacted with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) via the formation of charge-transfer (CT) complexes to give the thiadiazine derivative 19.The azomethine derivatives 1a-f reacted with both DDQ and 2,3-dicyano-1,4-naphthoquinone (DCNQ) via CT complexation to afford the bisazines 10a-f, the thiadiazole derivatives 11a-f and DDQ-H2 (12) as well as DCNQ-H2 (13).The mechanism of the formation of products 10-13 and 19 is discussed. - Keywords: charge-transfer complex; 1,3,4-thiadiazoles; 1,3,4-thiadiazines; dithiocarbazates; quinone.
- Hassan, Alaa A.
-
p. 424 - 428
(2007/10/02)
-