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CAS

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192725-12-5

1,2-Acridinediol, 1,2-dihydro-, (1R,2S)- (9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

192725-12-5

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192725-12-5 Usage

Category

Acridine derivatives

Physical Appearance

White to off-white powder

Potential Pharmaceutical and Biological Properties

Antimicrobial activity
Antiviral activity

Known as

Potent inhibitor of tartrate-resistant acid phosphatase
Enzyme involved in bone remodeling

Investigated for

Potential use in cancer therapy
Inhibits the growth of cancer cells

Research Status

More research needed to fully understand potential applications and effects

Check Digit Verification of cas no

The CAS Registry Mumber 192725-12-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,2,7,2 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 192725-12:
(8*1)+(7*9)+(6*2)+(5*7)+(4*2)+(3*5)+(2*1)+(1*2)=145
145 % 10 = 5
So 192725-12-5 is a valid CAS Registry Number.

192725-12-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (1R,2S)-1,2-dihydroacridine-1,2-diol

1.2 Other means of identification

Product number -
Other names (1R,2S)-1,2-Dihydro-acridine-1,2-diol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:192725-12-5 SDS

192725-12-5Upstream product

192725-12-5Downstream Products

192725-12-5Relevant articles and documents

Multiple site dioxygenase-catalysed cis-dihydroxylation of polycyclic azaarenes to yield a new class of bis-cis-diol metabolites

Boyd, Derek R.,Sharma, Narain D.,Carroll, Jonathan G.,Allen, Christopher C. R.,Clarke, David A.,Gibson, David T.

, p. 1201 - 1202 (1999)

The enhanced stability of new mono-cis-dihydrodiol bacterial metabolites of tricyclic azaarenes has facilitated the dioxygenase-catalysed formation and isolation of the corresponding bis-cis-dihydrodiols (cis-tetraols) and a three step chemoenzymatic route to the derived arene oxide mammalian metabolites.

Biphenyl dioxygenase-catalysed cis-dihydroxylation of tricyclic azaarenes: Chemoenzymatic synthesis of arene oxide metabolites and furoquinoline alkaloids

Boyd, Derek R.,Sharma, Narain D.,Carroll, Jonathan G.,Loke, Pui L.,O'Dowd, Colin R.,Allen, Christopher C. R.

, p. 10944 - 10955 (2013/09/02)

Biotransformation of acridine, dictamnine and 4-chlorofuro[2,3-b]quinolone, using whole cells of Sphingomonas yanoikuyae B8/36, yielded five enantiopure cyclic cis-dihydrodiols, from biphenyl dioxygenase-catalysed dihydroxylation of the carbocyclic rings.

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