19282-55-4 Usage
Uses
Used in Pharmaceutical Industry:
4,5,6,7-Tetrafluoroindoline serves as a crucial building block for the synthesis of pharmaceutical intermediates. Its unique structure and fluorine content contribute to the development of new drugs with improved pharmacological properties, such as enhanced bioavailability and targeted action.
Used in Agrochemical Industry:
In agriculture, 4,5,6,7-Tetrafluoroindoline is utilized in the creation of agrochemicals. Its incorporation into these compounds can lead to the development of more effective and targeted pesticides, herbicides, and other agricultural chemicals that can improve crop protection and yield.
Used in Materials Science:
4,5,6,7-Tetrafluoroindoline also finds application in the field of materials science. It is used in the production of functional materials that may possess specialized properties, such as increased stability, resistance to environmental factors, or specific interactions with other molecules, which can be beneficial in various high-tech applications.
Overall, 4,5,6,7-Tetrafluoroindoline is a versatile and important chemical compound that plays a significant role across multiple industries, including medicine, agriculture, and materials science, due to its potential to enhance the performance and functionality of a wide array of products.
Check Digit Verification of cas no
The CAS Registry Mumber 19282-55-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,2,8 and 2 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 19282-55:
(7*1)+(6*9)+(5*2)+(4*8)+(3*2)+(2*5)+(1*5)=124
124 % 10 = 4
So 19282-55-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H5F4N/c9-4-3-1-2-13-8(3)7(12)6(11)5(4)10/h13H,1-2H2
19282-55-4Relevant articles and documents
The synthesis of 7,8,9,10-Tetrafluoroellipticine
James Gruver,Onyango, Evans O.,Gribble, Gordon W.
, p. 144 - 152 (2018/07/05)
We have synthesized a novel ellipticine analogue, 7,8,9,10-Tetrafluoroellipticine, in nine steps from hexafluorobenzene and ethyl cyanoacetate, via 1-(phenysulfonyl)-4,5,6,7-Tetrafluoroindole. The key step is lithiation of the indole and subsequent coupling with 3,4-pyridinedicarboxylic acid anhydride to afford a ketolactam. Reaction of the lactam with methyllithium followed by reduction with sodium borohydride yields 7,8,9,10-Tetrafluoroellipticine. formula presented.
Polyfluoroaralkylamines: an improved synthesis of 4,5,6,7-tetrafluoroindole
Filler, Robert,Chen, Wei,Woods, Sarah M.
, p. 95 - 100 (2007/10/02)
Tetrafluoroindole (5), a precursor for potential biologically-active compounds, was prepared previously in a four-step synthesis from C6F6.However, catalytic reduction of pentafluorophenylacetonitrile (2) to 2-pentafluorophenylethyl amine (3) is accompanied by a significant amount of a secondary amine, which, like 3, undergoes cyclization to an indoline and subsequent dehydrogenation to a new indole 8.The side-reaction in the reduction of 2 to 3 is obviated by the use of LiAlH4/AlCl3 (1:1).The final aromatization to yield 5 is vastly improved by replacing MnO2 with DDQ. - Keywords: Polyfluoroaralkylamines; Synthesis; Tetrafluoroindole; NMR spectroscopy; IR spectroscopy
