Welcome to LookChem.com Sign In|Join Free

CAS

  • or

19313-28-1

13,14-DIHYDROPROSTAGLANDIN E1 (13,14-dihydro PGE1) is a biologically active metabolite of Prostaglandin E1 (PGE1) with comparable potency to the parent compound. It is characterized by its ability to inhibit ADP-induced platelet aggregation in human platelet-rich plasma (PRP) and washed platelets, making it a significant player in the realm of blood clotting and cardiovascular health. Additionally, 13,14-dihydro PGE1 has been shown to activate adenylate cyclase in NCB-20 hybrid cells, further contributing to its biological activities.

19313-28-1 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 19313-28-1 Structure

  • Basic information

    1. Product Name: 13,14-DIHYDROPROSTAGLANDIN E1
    2. Synonyms: 9-OXO-11ALPHA,15S-DIHYDROXY-PROSTAN-1-OIC ACID;13,14-DIHYDROPROSTAGLANDIN E1;PGE0;13,14-Dihydroprostaglandinee1;13,14-dihydro PGE1;7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoctyl]-5-oxocyclopentyl]heptanoic acid;(11R)-11α,15α-Dihydroxy-9-oxoprostan-1-oic acid;13,14-Dihydro-prostaglandin E1 (PGE0)
    3. CAS NO:19313-28-1
    4. Molecular Formula: C20H36O5
    5. Molecular Weight: 356.5
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 19313-28-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 541.4°Cat760mmHg
    3. Flash Point: 295.3°C
    4. Appearance: /
    5. Density: 1.075g/cm3
    6. Vapor Pressure: 5.56E-14mmHg at 25°C
    7. Refractive Index: 1.499
    8. Storage Temp.: Refrigerator, under inert atmosphere
    9. Solubility: Ethyl Acetate, Methanol, Tetrahydrofuran
    10. Stability: Volatile
    11. CAS DataBase Reference: 13,14-DIHYDROPROSTAGLANDIN E1(CAS DataBase Reference)
    12. NIST Chemistry Reference: 13,14-DIHYDROPROSTAGLANDIN E1(19313-28-1)
    13. EPA Substance Registry System: 13,14-DIHYDROPROSTAGLANDIN E1(19313-28-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 19313-28-1(Hazardous Substances Data)

19313-28-1 Usage

Uses

Used in Pharmaceutical Applications:
13,14-DIHYDROPROSTAGLANDIN E1 is used as a therapeutic agent for promoting cardiovascular health. Its ability to inhibit platelet aggregation makes it a valuable compound in the prevention and treatment of conditions related to blood clotting, such as thrombosis and atherosclerosis.
Used in Research Applications:
In the field of scientific research, 13,14-DIHYDROPROSTAGLANDIN E1 is used as a research tool to study the mechanisms underlying platelet aggregation and blood clotting. Its potent inhibitory effects on ADP-induced platelet aggregation make it a useful compound for investigating the roles of various signaling pathways and enzymes in these processes.
Used in Drug Development:
13,14-DIHYDROPROSTAGLANDIN E1 serves as a lead compound in the development of new drugs targeting blood clotting disorders. Its potent anti-aggregatory effects and activation of adenylate cyclase provide a foundation for designing novel therapeutics that can potentially offer improved efficacy and safety profiles compared to existing treatments.
Used in Diagnostic Applications:
13,14-DIHYDROPROSTAGLANDIN E1 can be employed in the development of diagnostic tests for assessing platelet function and blood clotting propensity. Its ability to inhibit platelet aggregation can be utilized to identify individuals at risk for developing thrombotic disorders or to monitor the effectiveness of antiplatelet therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 19313-28-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,3,1 and 3 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 19313-28:
(7*1)+(6*9)+(5*3)+(4*1)+(3*3)+(2*2)+(1*8)=101
101 % 10 = 1
So 19313-28-1 is a valid CAS Registry Number.
InChI:InChI=1/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h15-17,19,21,23H,2-14H2,1H3,(H,24,25)/t15-,16+,17+,19+/m0/s1

19313-28-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 13,14-DIHYDROPROSTAGLANDIN E1

1.2 Other means of identification

Product number -
Other names PGE0

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19313-28-1 SDS

19313-28-1Upstream product

19313-28-1Downstream Products

19313-28-1Relevant articles and documents

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 19313-28-1