193904-60-8

Basic information

• Product Name: 1,2-Benzisothiazole, 6-ethyl-2,3-dihydro-3-methyl-, 1,1-dioxide (9CI)
• Synonyms: 1,2-Benzisothiazole, 6-ethyl-2,3-dihydro-3-methyl-, 1,1-dioxide (9CI)
• CAS NO: 193904-60-8
• Molecular Formula: C10H13NO2S
• Molecular Weight: 211.28072
• Product Categories: ALCOHOL
• Mol File: 193904-60-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-Benzisothiazole, 6-ethyl-2,3-dihydro-3-methyl-, 1,1-dioxide (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzisothiazole, 6-ethyl-2,3-dihydro-3-methyl-, 1,1-dioxide (9CI)(193904-60-8)
• EPA Substance Registry System: 1,2-Benzisothiazole, 6-ethyl-2,3-dihydro-3-methyl-, 1,1-dioxide (9CI)(193904-60-8)

Safety Data

• Hazardous Substances Data: 193904-60-8(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic organic compound

Structure

Thiazole ring fused to a benzene ring

Applications

a. Manufacturing of pharmaceuticals
b. Manufacturing of agrochemicals
c. Building block for various biologically active compounds
d. Potential applications in materials science and research

Precautions

a. Handle with care due to potential health and environmental risks
b. Proper handling and disposal required to minimize risks

Upstream product

• 193904-59-5 {[(2,5-diethylphenyl)sulfonyl]imino}phenyl-λ³-iodane 
• 91252-29-8 2,5-diethylbenzenesulfonamide 

Relevant articles and documents

Chemoselective, enzymatic C-H bond amination catalyzed by a cytochrome P450 containing an Ir(Me)-PIX cofactor

Cytochrome P450 enzymes have been engineered to catalyze abiological C-H bond amination reactions, but the yields of these reactions have been limited by low chemoselectivity for the amination of C-H bonds over competing reduction of the azide substrate t

Intramolecular C-H amination with sulfonyl azides

Cobalt (II) complexes of porphyrins are effective catalysts for intramolecular nitrene insertion of C—H bonds with arylsulfonyl azides. The cobalt-catalyzed process can proceed efficiently under mild and neutral conditions in low catalyst loading without

Cobalt-catalyzed intramolecular C-H amination with arylsulfonyl azides

(Chemical Equation Presented) Cobalt complexes of porphyrins are effective catalysts for intramolecular C-H amination with arylsulfonyl azides. The cobalt-catalyzed process can proceed efficiently under mild and neutral conditions in low catalyst loading

Rhodium(II)-catalyzed nitrene transfer with phenyliodonium ylides

The [Rh2(OAc)4]-catalyzed decomposition of NsN=IPh {[N-(p-nitrobenzenesulfonyl)imino]phenyl-iodinane} affords aziridines in the presence of olefins and insertion products with compounds having activated CH bonds. The aziridination is stereospecific, and the insertion proceeds with retention of configuration. With chiral Rh(II) complexes, enantioenriched products result. A one-step mechanism involving a metal-complexed nitrene is proposed for both reactions.

Rhodium(II)-Catalyzed CH Insertions with imino>phenyl-λ3-iodane

The catalyzed decomposition of imino>phenyl-λ3-iodane (NsN=IPh) resulted in formal insertions into CH bonds, activated by phenyl or vinyl groups, or by O-substituents.Scope and limitations of the reaction were investigated.Yields of up to 84percent were achieved in the most favorable cases.Yields were enhanced by electron-releasing substituents and decreased by steric hindrance.Aziridination competed with allylic insertion with olefinic substrates.The insertion reaction proceeded with retention of configuration.With chiral RhII catalysts, a modest asymmetric induction was observed.A mechanism involving direct insertion by a Rh-complexed nitrene into the CH bond is proposed.