Synthesis and pharmacology of two new histamine receptor antagonists related to ranitidine
Pyridyl and 1,6-dihydropyridyl ranitidine analogues 1 and 2 were obtained by applying an improved modification of ranitidine synthesis. Compound 1 shows a selective H2 antagonistic activity while compound 2 is a non-selective histamine antagonist.
Navarro,Almeida,Anaya,Moran,Grande,Caballero,Palacios,Montero,San Roman
p. 12 - 15
(2007/10/02)
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