194874-16-3Relevant articles and documents
One-pot synthesis of trisubstituted ureas from achloroaldoxime O-methanesulfonates and secondary amines
Kaeobamrung, Juthanat,Lanui, Asan,Mahawong, Sirinad,Duangmak, Witthawin,Rukachaisirikul, Vatcharin
, p. 58587 - 58594 (2018/02/19)
Trisubstituted ureas can be synthesized in a one-pot fashion from bench-stable a-chloroaldoxime Omethanesulfonates and secondary amines under mild reaction conditions. Two practical protocols have been developed to achieve various urea syntheses from both secondary aromatic amines and aliphatic amines.
Novel quenchers for solution phase parallel synthesis
Nikam, Sham S.,Kornberg, Brian E.,Ault-Justus, Stephanie E.,Rafferty, Michael F.
, p. 1121 - 1124 (2007/10/03)
The bifunctionality of amino acids can be exploited by utilizing them as quenchers in rapid solution phase parallel synthesis. The amino group was used to covalently trap the excess electrophiles, whereas the carboxylic acid moiety was used to solubilize