Welcome to LookChem.com Sign In|Join Free

CAS

  • or

194928-82-0

(6R,7R)-3-[4-(Carbamoylmethyl)thiazol-2-ylsulfanyl]-7-(2-phenylacetamido)-3-cephem-4-carboxylic acid is a cephalosporin antibiotic belonging to the beta-lactam class of antibiotics. It features a thiazole ring and a cephem ring in its structure, which contribute to its potent antibacterial activity. (6R,7R)-3-[4-(Carbamoylmethyl)thiazol-2-ylsulfanyl]-7-(2-phenylacetamido)-3-cephem-4-carboxylic acid is effective against a broad spectrum of gram-positive and gram-negative bacteria, making it a valuable asset in the medical field for treating various bacterial infections.

194928-82-0 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 194928-82-0 Structure

  • Basic information

    1. Product Name: (6R,7R)-3-[4-(Carbamoylmethyl)thiazol-2-ylsulfanyl]-7-(2-phenylacetamido)-3-cephem-4-carboxylic acid
    2. Synonyms: FR-193879
    3. CAS NO:194928-82-0
    4. Molecular Formula: C20H18N4O5S3
    5. Molecular Weight: 490.58226
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 194928-82-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (6R,7R)-3-[4-(Carbamoylmethyl)thiazol-2-ylsulfanyl]-7-(2-phenylacetamido)-3-cephem-4-carboxylic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: (6R,7R)-3-[4-(Carbamoylmethyl)thiazol-2-ylsulfanyl]-7-(2-phenylacetamido)-3-cephem-4-carboxylic acid(194928-82-0)
    11. EPA Substance Registry System: (6R,7R)-3-[4-(Carbamoylmethyl)thiazol-2-ylsulfanyl]-7-(2-phenylacetamido)-3-cephem-4-carboxylic acid(194928-82-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 194928-82-0(Hazardous Substances Data)

194928-82-0 Usage

Uses

Used in Pharmaceutical Industry:
(6R,7R)-3-[4-(Carbamoylmethyl)thiazol-2-ylsulfanyl]-7-(2-phenylacetamido)-3-cephem-4-carboxylic acid is used as an antibiotic for the treatment of various bacterial infections. Its application is based on its ability to inhibit bacterial cell wall synthesis, thereby preventing the growth and proliferation of bacteria.
Used in Clinical Settings:
In the clinical setting, (6R,7R)-3-[4-(Carbamoylmethyl)thiazol-2-ylsulfanyl]-7-(2-phenylacetamido)-3-cephem-4-carboxylic acid is used as a therapeutic agent to combat bacterial infections. Its effectiveness against a wide range of bacteria makes it a crucial component in the arsenal of antibiotics used by healthcare professionals to treat patients with bacterial infections.

Check Digit Verification of cas no

The CAS Registry Mumber 194928-82-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,9,2 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 194928-82:
(8*1)+(7*9)+(6*4)+(5*9)+(4*2)+(3*8)+(2*8)+(1*2)=190
190 % 10 = 0
So 194928-82-0 is a valid CAS Registry Number.

194928-82-0Downstream Products

194928-82-0Relevant articles and documents

Studies on anti-Helicobacter pylori agents. Part 3: A novel, efficacious cephem derivative, FR193879

Yoshida, Yoshiki,Matsuda, Keiji,Sasaki, Hiroshi,Matsumoto, Yoshimi,Matsumoto, Satoru,Tawara, Shuichi,Takasugi, Hisashi

, p. 2627 - 2631 (2007/10/03)

The synthesis, therapeutic efficacy against H. pylori, and preliminary safety of the novel cephem derivative, FR193879 (8a) are described. Compound 8a having a (4-carbamoylmethylthiazol-2-yl)thio moiety at the 3-position and a phenylacetamido at the 7-position was found to have good safety showing a nontoxic dose of 100mg/kg in dogs in a 4-week repeat dose toxicity study and extremely potent therapeutic efficacy against H. pylori, showing 30 times superior activity compared to AMPC, and did not display cross-resistance with CAM or MNZ.

Cephem compounds and pharmaceutical use thereof

-

, (2008/06/13)

PCT No. PCT/JP97/00280 Sec. 371 Date Aug. 12, 1998 Sec. 102(e) Date Aug. 12, 1998 PCT Filed Feb. 5, 1997 PCT Pub. No. WO97/29111 PCT Pub. Date Aug. 14, 1997This invention relates to new cephem compound represented by the following general formula (I): whe

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 194928-82-0