195059-10-0

Basic information

• Product Name: 2H-Indole-2-carboxylic acid, 3,5-dihydro-6-hydroxy-5-oxo-, methyl ester, (S)- (9CI)
• Synonyms: 2H-Indole-2-carboxylic acid, 3,5-dihydro-6-hydroxy-5-oxo-, methyl ester, (S)- (9CI)
• CAS NO: 195059-10-0
• Molecular Formula: C10H9NO4
• Molecular Weight: 207.18276
• Product Categories: ALCOHOL
• Mol File: 195059-10-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2H-Indole-2-carboxylic acid, 3,5-dihydro-6-hydroxy-5-oxo-, methyl ester, (S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Indole-2-carboxylic acid, 3,5-dihydro-6-hydroxy-5-oxo-, methyl ester, (S)- (9CI)(195059-10-0)
• EPA Substance Registry System: 2H-Indole-2-carboxylic acid, 3,5-dihydro-6-hydroxy-5-oxo-, methyl ester, (S)- (9CI)(195059-10-0)

Safety Data

• Hazardous Substances Data: 195059-10-0(Hazardous Substances Data)

Upstream product

• 40611-00-5 DL-3-(3,4-dihydroxyphenyl)alanine methyl ester hydrochloride 
• 7101-51-1 (+/-)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine 
• 63-84-3 dopa 
• 7101-51-1 L-DOPA methyl ester 

Relevant articles and documents

Inhibition of macrophage migration inhibitory factor (MIF) tautomerase activity by dopachrome analogs

A macrophage migration inhibitory factor (MIF) dopachrome tautomerization assay was employed for identification of MIF inhibitors. One group of dopachrome analogs was identified which inhibits MIF tautomerase activity. In particular, the analogs with a leaving group at β position displayed activity at a concentration of tenfold less than that of the MIF-substrate. These findings could lead to a better understanding of MIF biological activities and the development of agents for the treatment of MIF related diseases.