New synthetic retinoids obtained by palladium-catalyzed tandem cyclisation-hydride capture process
A new series of conformationally restricted retinoids (3-aryl-3-methyl- 2,3-dihydrobenzofurans) have been prepared through a palladium-catalyzed tandem cyclisation-hydride capture. The use of enantiopure BINAP-Pd catalyst allowed asymmetric synthesis of bioactive molecules.
Diaz, Philippe,Gendre, Fabrice,Stella, Lucien,Charpentier, Bruno
p. 4579 - 4590
(2007/10/03)
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