- PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF
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Provided herein are pentafluorobenzenesulfonamide compounds of Formula (I), pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases. These compounds are covalent small molecule inhibitors,
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Paragraph 00249
(2021/05/29)
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- Synthesis, biodistribution and micro-PET imaging of radiolabeled antimitotic agent T138067 analogues
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Radiolabeled antimitotic agents [11C]T138067 and [ 18F]T138067 have been synthesized for evaluation as new potential positron emission tomography (PET) biomarkers for cancer imaging. In vivo biodistribution and micro-PET imaging of [
- Fei, Xiangshu,Zheng, Qi-Huang,Wang, Ji-Quan,Stone, K. Lee,Martinez, Tanya D.,Miller, Kathy D.,Sledge, George W.,Hutchins, Gary D.
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p. 1247 - 1251
(2007/10/03)
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- Pentafluorobenzenesulfonamides and analogs
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The invention provides methods and compositions relating to novel pentafluorophenylsulfonamide derivatives and analogs and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particularly cancer, vascular restenosis, microbial infections, and psoriasis, or as lead compounds for the development of such agents. The compositions include compounds of the general formula I:
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- Pentafluorobenzenesulfonamides and analogs
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The invention provides methods and compositions relating to novel pentafluorophenylsulfonamide derivatives and analogs and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particularly atherosclerosis and hypercholesterolemia, or as lead compounds for the development of such agents. The compositions include compounds of the general formula I: STR1
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