196303-47-6

Basic information

• Product Name: 1H-INDOLE,7-ETHYL-2,3-DIHYDRO-
• Synonyms: 1H-INDOLE,7-ETHYL-2,3-DIHYDRO-;7-ethyl-2,3-dihydro-1H-indole
• CAS NO: 196303-47-6
• Molecular Formula: C10H13N
• Molecular Weight: 147.22
• Mol File: 196303-47-6.mol

Chemical Properties

• Boiling Point: 252.8±25.0 °C(Predicted)
• Appearance: /
• Density: 0.998±0.06 g/cm3(Predicted)
• PKA: 5.01±0.20(Predicted)
• CAS DataBase Reference: 1H-INDOLE,7-ETHYL-2,3-DIHYDRO-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-INDOLE,7-ETHYL-2,3-DIHYDRO-(196303-47-6)
• EPA Substance Registry System: 1H-INDOLE,7-ETHYL-2,3-DIHYDRO-(196303-47-6)

Safety Data

• Hazardous Substances Data: 196303-47-6(Hazardous Substances Data)

Usage

Chemical Class

Indole derivatives

Appearance

Colorless to light yellow liquid

Odor

Strong, floral

Usage

Production of fragrances and perfumes

Medical Applications

Potential antioxidant and anti-inflammatory properties

Chemical Industry Importance

Precursor to various drugs and pharmaceuticals, used as an intermediate

Upstream product

• 22867-74-9 7-ethyl-1H-indole 

Relevant articles and documents

Selective reduction of condensed N-heterocycles using water as a solvent and a hydrogen source

The reduction of unprotected indoles and quinolines is described using water as a hydrogen source. The method is based on the application of a RANEY type Ni-Al alloy in an aqueous medium. During the reaction the Al content of the alloy, used as reductants, reacts with water in situ providing hydrogen and a RANEY Ni catalyst, thus the alloy serves as a hydrogen generator as well as a hydrogenation catalyst. The simplicity and efficacy of the method are illustrated by the selective reduction of a variety of substituted indoles and quinolines to indolines and tetrahydroquinolines, respectively.

Heterogeneous catalytic hydrogenation of unprotected indoles in water: A green solution to a long-standing challenge

An environmentally benign procedure for the hydrogenation of unprotected indoles is described. The hydrogenation reaction is catalyzed by Pt/C and activated by p-toluenesulfonic acid in water as a solvent. The efficacy of the method is illustrated by the hydrogenation of a variety of substituted indoles to their corresponding indolines which were obtained in excellent yields.

Process for dyeing keratinous fibers with aminoindoles and oxidation dye precursors at basic Ph's and dyeing agents

The invention relates to a process for dyeing keratinous fibres, which consists in applying to these fibres a composition containing, in a suitable medium for dyeing, at least one coupler of formula: STR1 where R1 denotes hydrogen or alkyl, R2 and R3 denote hydrogen, alkyl, COOR' where R' is alkyl or hydrogen, at least one of the groups R2 and R3 denoting hydrogen, R4 denotes hydrogen, alkyl, hydroxyalkyl, polyhydroxyalkyl or aminoalkyl, Z1 and Z2 denote hydrogen, alkyl, hydroxyl, halogen, alkoxy, at least one of the groups Z1 and Z2 is other than hydrogen at least one oxidation dye precursor, at least one oxidizing agent, the pH of the composition applied to the fibres being higher than 7.

Methods for dyeing keratinous fibers with compositions which contain aminoindole couplers, oxidation dye precursors, and oxidizing agents at acid pHs

A method for dyeing keratin fibers, wherein a composition is applied to said fibers which contains, in a suitable dyeing medium, at least one coupler having formula (I) STR1 wherein R1 is hydrogen or alkyl; R2 and R3 are hydrogen, alkyl, COOR', where R' is alkyl or hydrogen; R4 is hydrogen, hydroxyalkyl, alkyl, polyhydroxyalkyl or acetyl or aminoalkyl wherein the amine may be mono- or disubstituted by alkyl; Z1 and Z2 are hydrogen, alkyl, hydroxy, halogen, alkoxy or a salt thereof; at least one precursor of an oxidation hair dye; and at least one oxidizing agent, the pH of the composition applied to the fibers being less than 7.