197448-76-3 Usage
Derived from
pyridine
Contains
a thione functional group
Common uses
fungicide in shampoos and skin creams
Effective against
dandruff and seborrheic dermatitis
Also has
antibacterial properties
Used in some personal care products
to treat acne
Caution
use according to manufacturer's instructions to avoid adverse effects
Check Digit Verification of cas no
The CAS Registry Mumber 197448-76-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,7,4,4 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 197448-76:
(8*1)+(7*9)+(6*7)+(5*4)+(4*4)+(3*8)+(2*7)+(1*6)=193
193 % 10 = 3
So 197448-76-3 is a valid CAS Registry Number.
197448-76-3Relevant articles and documents
Discovery of Ro 48-5695: A potent mixed endothelin receptor antagonist optimized from Bosentan
Neidhart, Werner,Breu, Volker,Burri, Kaspar,Clozel, Martine,Hirth, Georges,Klinkhammer, Uwe,Giller, Thomas,Ramuz, Henri
, p. 2223 - 2228 (2007/10/03)
Implementation of a pyridylcarbamoyl group and an isopropylpyridylsulfonamide substituent as key components in the scaffold of Bosentan resulted in the identification of the potent orally active endothelin receptor antagonist Ro 48-5695. It shows affinities for ET(A) and ET(B) receptors in the low nanomolar range and high functional antagonistic potency in vitro.