19754-80-4

Basic information

• Product Name: (5-Ethylisoxazol-3-yl)amine
• Synonyms: (5-Ethylisoxazol-3-yl)amine;3-Amino-5-ethylisoxazole
• CAS NO: 19754-80-4
• Molecular Formula: C₅H₈N₂O
• Molecular Weight: 112.12982
• Mol File: 19754-80-4.mol

Chemical Properties

• Melting Point: 71-72℃
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: (5-Ethylisoxazol-3-yl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: (5-Ethylisoxazol-3-yl)amine(19754-80-4)
• EPA Substance Registry System: (5-Ethylisoxazol-3-yl)amine(19754-80-4)

Safety Data

• Hazardous Substances Data: 19754-80-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Development:
(5-Ethylisoxazol-3-yl)amine is used as a pharmaceutical intermediate for the synthesis of various drug candidates. Its unique structure allows it to be a versatile component in the development of new medications, particularly those targeting specific biological pathways or receptors.
Used in Organic Synthesis:
In the field of organic synthesis, (5-Ethylisoxazol-3-yl)amine is used as a building block to create more complex chemical compounds. Its isoxazole ring and amine group provide a foundation for the formation of a wide range of molecules with diverse properties and potential applications.
Used in Medicinal Chemistry Research:
(5-Ethylisoxazol-3-yl)amine is utilized in medicinal chemistry research to explore its potential as a lead compound for the development of new therapeutic agents. Its chemical properties and interactions with biological targets are studied to understand its efficacy and safety in potential drug applications.
Used in Chemical Manufacturing:
(5-Ethylisoxazol-3-yl)amine may also be used in the chemical manufacturing industry as an intermediate in the production of other chemical products. Its ability to be modified and incorporated into various compounds makes it a valuable component in the synthesis of a range of chemical substances.

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Downstream Products

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Relevant articles and documents

Preparation method 3 -amino -5 -alkyl isoxazole

The invention discloses a preparation method of 3-amino-5-alkyl isoxazole, realizes preparation through two steps and belongs to the technical field of organic chemistry. By starting from easily obtained aldehyde, after the addition with acetonitrile under the existence of metal alkali, an intermediate of hydroxy nitrile is obtained; then, the hydroxy nitrile reacts with hydroxylamine; ring closing reaction is performed under the existence of Lewis acid; after autoxidation, the 3-amino-5-alkyl isoxazole is obtained. The raw materials in the reaction process are very commons; chloroform or tetrachloromethane in a traditional method is avoided; potential industrial amplification prospects are realized.

HETEROARYL PYRIDONE AND AZA-PYRIDONE COMPOUNDS AS INHIBITORS OF BTK ACTIVITY

Heteroaryl pyridone and aza-pyridone compounds of Formula I are provided, where one or two of X, X, and Xare N, and including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I foranddiagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

HETEROCYCLIC COMPOUNDS CONTAINING AN INDOLE CORE

Disclosed are novel compounds which inhibit RSK, methods of making such compounds and pharmaceutical compositions comprising such compounds. Also disclosed are methods of treating RSK2 regulated disorders using compounds of the invention.

QUINOLINE DERIVATIVES

The invention concerns quinoline derivatives of Formula I or a pharmaceutically-acceptable salt thereof, wherein each of X1, p, R1, q, R2, R3, R4, R5Ring A, r and R6 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders.

1,3-DISUBSTITUTED AZETIDINE DERIVATIVES FOR USE AS CCR-3 RECEPTOR ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISEASES

Compounds of formula Ia or Ib in free or salt form, wherein Ar, X1, X2, m, R1, Q, Y, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by CCR-3, for example an inflammatory or allergic cond