Highly regioselective and stereoselective synthesis of C-Aryl glycosidesvianickel-catalyzedortho-C-H glycosylation of 8-aminoquinoline benzamides
C-Aryl glycosides are of high value as drug candidates. Here a novel and cost-effective nickel catalyzedortho-CAr-H glycosylation reaction with high regioselectivity and excellent α-selectivity is described. This method shows great functional group compatibility with various glycosides, showing its synthetic potential. Mechanistic studies indicate that C-H activation could be the rate-determining step.
Synthesis of Rhamnolipid Derivatives Containing Ester Isosteres
Rhamnolipids are biosurfactants with many applications, arising from their inherent biological activity and their potential as bioremediation agents. Herein, we report the synthesis of four rhamnolipid derivatives in which the ester linkage connecting the
Lowary, Todd L.,Wang, Lei
supporting information
p. 9633 - 9637
(2020/12/21)
Facile glycosylation strategy with two-stage activation of allyl glycosyl donors. Application to concise synthesis of Shigella flexneri serotype y O-antigen
A practical, useful glycosylation method employing only allyl glycoside building blocks has been developed. The donor's glycosylation reactivity is turned on via isomerization of its anomeric allyl protecting group into the corresponding prop-1-enyl moiet
Wang, Yun,Zhang, Xin,Wang, Pengfei
supporting information; experimental part
p. 4322 - 4328
(2010/11/18)
Total synthesis of tricolorin A
Tricolorin A (1) is a novel tetrasaccharide macrolactone that is a natural herbicide. In this paper is reported a total synthesis of 1. Coupling of hydroxy ester 18 with D-fucosyl trichloroacetimidate 23 gave fucoside 24. Removal of he C-2 pivaloyl group
Larson, Daniel P.,Heathcock, Clayton H.
p. 8406 - 8418
(2007/10/03)
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