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19810-79-8

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1,4-DISUBSTITUTED ISOQUINILONE DERIVATIVES AS RAF-KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES
This invention relates to compounds of formula (I) wherein the variable substituents are described herein. The compounds are useful for the treatment of conditions and diseases characterized by an aberrant MAP kinase signaling pathway, such as cancer.
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Page/Page column 49

(2010/02/11)

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663194-10-3
4-(4-bromopyrimidin-2-yl)morpholine

Chemical Properties

Density: 1.41
Storage Temp.:Sealed in dry,Room Temperature
PSA: 58.48000
LogP: 0.08380

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