Rapid and efficient microwave-assisted synthesis of 4-, 5-, 6- and 7-azaindoles
Under microwave irradiation conditions, the imines/enamines formed between aminopyridines and ketones are converted in moderate to good yields to the corresponding 4-, 5-, 6- or 7-azaindoles via the Hegedus-Mori-Heck reaction (intramolecular Heck reaction
Lachance, Nicolas,April, Myriam,Joly, Marc-Andre
p. 2571 - 2577
(2007/10/03)
Photochemistry of polyhalogenated heterocyclic enaminones: Competition between cyclization and dehalogenation
Photochemistry of polyhalogenated enaminones is described under various conditions to give functionalized tetrahydroazacarbazolone (9, 15). Starting enaminones (2, 7, 14) also underwent competitive dehalogenations creating a set of secondary products. Mec
Palladium-catalyzed synthesis of 1,2-dihydro-4(3H)-carbazolones. Formal total synthesis of murrayaquinone A
Two sequential palladium-catalyzed reactions are the key steps in a novel synthetic route to 1,2-dihydro-4(3H)-carbazolones. The steps are an intermolecular Stille cross-coupling followed by a reductive N-heteroannulation. A formal total synthesis of murrayaquinone A, employing this sequence, is reported.
Scott, Tricia L.,S?derberg, Bj?rn C. G.
p. 6323 - 6332
(2007/10/03)
Compared reactivity of heterocyclic enaminones: Photochemical and palladium catalyzed synthesis of 6,7,8,9-tetrahydro-5H-pyridol[3,2-b]indol- 9-ones