Synthesis, spectroscopy and computational studies of selected hydroxyquinoline carboxylic acids and their selected fluoro-, thio-, and dithioanalogues
The faster and more efficient new synthetic methodologies of crystalline hydroxyquinoline carboxylic acids and their fluoro-, thio- and dithioanalogues were elaborated. The FTIR, multinuclear NMR, UV-Vis and single crystal X-ray characteristics of the series of quinoline carboxylic acids have been determined experimentally and rationalized on the basis of DFT calculation method with B3LYP functional.
Nycz, Jacek E.,Malecki, Grzegorz J.
p. 159 - 168
(2013/02/22)
Aroylaniline compounds, pharmaceutical compositions, and methods of using same to inhibit viral activity
Aroylaniline compounds which exhibit anti-retroviral activity, pharmaceutical compositions containing such aroylaniline compounds, and methods for treating a retroviral-infected host comprising administering an antiviral effective amount of an aroylaniline compound to a host.
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(2008/06/13)
Synthesis and NMR study of two lipophilic iron(III) sequestering agents based on 8-hydroxyquinoline; H-bonding and conformationsl changes
The synthesis of two tripodal iron chelating agents based on 8-hydroxyquinoline is described. The ligands consist of tris(2-aminoethylamine) (spacer) linked in 2- or 7-position to three 8-hydroxyquinoline units (allowing the complexation of iron). NMR stu
Caris,Baret,Pierre,Serratrice
p. 4659 - 4672
(2007/10/03)
SYNTHESIS OF QUINOLIN-8-OL-7-CARBOXYLIC ACID BY CARBOXYLATION OF QUINOLIN-8-OL
A study has been made of carboxylation of quinolin-8-ol and its alkali metal salts.The optimal carboxylation conditions have been determined, which ensure a yield of quinolin-8-ol-7-carboxylic acid as high as 59.5percent based on the starting material.
Ragulin, V. V.,Ragulina, I. R.,Shakirov, L. G.
p. 1086 - 1088
(2007/10/03)
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