19842-07-0

Basic information

• Product Name: 2-Amino-5-ethyl-pyridine
• Synonyms: 2-Amino-5-ethyl-pyridine;5-ETHYL-PYRIDIN-2-YLAMINE;5-ethyl-2-PyridinaMine;5-ethylpyridin-2-aMine;2-Pyridinamine, 5-ethyl-
• CAS NO: 19842-07-0
• Molecular Formula: C₇H₁₀N₂
• Molecular Weight: 122.17
• Product Categories: pharmacetical
• Mol File: 19842-07-0.mol

Chemical Properties

• Boiling Point: 90-92 °C(Press: 3 Torr)
• Appearance: /
• Density: 1.037±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 7.06±0.13(Predicted)
• CAS DataBase Reference: 2-Amino-5-ethyl-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-5-ethyl-pyridine(19842-07-0)
• EPA Substance Registry System: 2-Amino-5-ethyl-pyridine(19842-07-0)

Safety Data

• Hazardous Substances Data: 19842-07-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
2-Amino-5-ethyl-pyridine is used as a key intermediate in the synthesis of a variety of complex chemical compounds. Its presence in the molecular structure of these compounds often contributes to their unique properties and potential applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2-Amino-5-ethyl-pyridine is utilized as a building block for the development of new drugs. Its structural versatility allows for the creation of molecules with specific therapeutic properties, making it an essential component in the design and synthesis of novel pharmaceutical agents.
Used in Agrochemical Industry:
2-Amino-5-ethyl-pyridine is employed as a precursor in the production of agrochemicals, such as pesticides and herbicides. Its role in the synthesis of these compounds is crucial for the development of effective and targeted agricultural products that can protect crops from pests and diseases.

Upstream product

• 110-86-1 pyridine 
• 14906-62-8 3-ethylpyridine N-oxide 
• 407-25-0 trifluoroacetic anhydride 
• 1072-97-5 5-bromo-2-pyridylamine 
• 557-20-0 diethylzinc 
• 62114-80-1 2-amino-5-ethenylpyridine 

Relevant articles and documents

Mild, General, and Regioselective Synthesis of 2-Aminopyridines from Pyridine N -Oxides via N -(2-Pyridyl)pyridinium Salts

A synthesis of 2-aminopyridines from pyridine N-oxides via their corresponding N-(2-pyridyl)pyridinium salts has been demonstrated and investigated. The reaction sequence features a highly regioselective conversion of the N-oxide into its pyridinium salt

SULFONYL-SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS ROR INHIBITOR

Provided is a sulfonyl-substituted bicyclic compound (A) which acts as a RORγ inhibitor, said compound has good RORγ inhibitory activity and is expected to be used for treating diseases mediated by a RORγ receptor in mammals.

NOVEL BICYCLIC HETEROCYCLIC COMPOUND

Provided are a novel compound having a superior inhibitory action on KAT-II, a production method thereof, use thereof, and a pharmaceutical composition containing the aforementioned compound and the like. A compound represented by the formula (I) or a pharmacologically acceptable salt thereof. wherein each symbol is as defined in the DESCRIPTION.

PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS

The present invention relates to a catalytic method for the conversion of amide-containing compouds by means of a build-in directing group and upon the action of a heteronucleophilic compound (in se an amine (RNH2 or RNHR') or an alcohol (ROH) or a thiol (RSH)) in the presence of a metal catalyst to respectively esters, thioesters, carbonates, thiocarbonates and to what is defined as amide-containing compounds (such as carboxamides, urea, carbamates, thiocarbamates). The present invention also relates to these amide-containing compounds having a build-in directing group (DG), as well as the use of such directing groups in the catalytic directed cleavage of N-DG amides with the use of heteronucleophiles (in se an amine (RNH2 or RNHR') or an alcohol (ROH) or thiol (RSH)).

PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided compounds of formula (I), wherein R1, R2, X1, X2 and n have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

TRIAZOLE COMPOUNDS AS LIPOXYGENASE INHIBITORS

There is provided compounds of formula (I) wherein W is an optionally substituted aryl or heteroaryl group, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15- lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

5,7-DIAMINOPYRAZOLO`4,3-D!PYRIMIDINES USEFUL IN THE TREATMENT OF HYPERTENSION

This invention relates to compounds of formula (I).

NITROGENOUS FUSED?RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF

The present invention provides a compound having an excellent inhibitory action on activation of STAT6 and a pharmaceutical composition thereof. Inparticular, it provides a compound represented by the following formula (I), a salt thereof or a hydrate of them. In the formula, X represents a nitrogen-containing condensed aromatic heterocyclic group such as imidazo[1,2-a]pyridine, benzimidazole, quinazoline, quinoline, or 2,1-benzisoxazole and has (R4)n as substituent groups; Y represents a C3-8 cycloalkyl group, C4-8 cycloalkenyl group, 5- to 14-membered non-aromatic heterocyclic group, C6-14 aromatic hydrocarbon cyclic group or 5- to 14-membered aromatic heterocyclic group; n in (R4)n is 0, 1, 2 or 3, and Z groups independently represent (1) hydrogen atom, (2) amino group, (3) halogen atom, (4) hydroxyl group, (5) nitro group, (6) cyano group, (7) azido group, (8) formyl group, (9) hydroxyamino group, (10) sulfamoyl group, (11) guanodino group, (12) oxo group, (13) C2-6 alkenyl group, (14) C1-6 alkoxy group, (15) C1-6 alkylhydroxyamino group, (16) halogenated C1-6 alkyl group, (17) halogenated C2-6 alkenyl group, (18) (i) C3-7cycloalkyl group, (ii) C3-7cycloalkenyl group, (iii) 5- to 14-membered non-aromatic heterocyclic group, each of which may have one or more substituent groups Q, or (19) formula -M1-M2-M3, R1 represents (1) hydrogen atom, (2) halogen atom, (3) hydroxyl group, (4) nitro group, (5) cyano group, (6) halogenated C1-6 alkyl group, (7) C2-6 alkyl group substituted with a hydroxyl or cyano group, (8) C2-6 alkenyl group, or (9) formula -L1-L2-L3, and R2 represents a hydrogen atom or a protecting group; and R3 represents a hydrogen atom, halogen atom, cyano group, amino group, C1-4 alkyl group or halogenated C1-4 alkyl group.

Substituted 2-aminopyridines as inhibitors of nitric oxide synthase

Substituted 2-aminopyridine compounds of Formula (I) and pharmaceutically acceptable salts which have been found useful in the treatment of nitric oxide synthase mediated diseases and disorders. STR1

3-TETRAZOLO-5,6,7,8-SUBSTITUTED PYRIDO[1,2-a]PYRIMIDIN-4-ONES

A novel series of optionally substituted 3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-ones is provided for use as inhibitors of allergic reactions. The compounds exhibit antiallergy activity by both oral and parenteral routes of administration