19850-36-3

Basic information

• Product Name: 6-({[2-(methylsulfanyl)phenyl]amino}methylidene)cyclohexa-2,4-dien-1-one
• CAS NO: 19850-36-3
• Molecular Formula: C₁₄H₁₃NOS
• Molecular Weight: 243.3241
• Mol File: 19850-36-3.mol

Chemical Properties

• Boiling Point: 394.1°C at 760 mmHg
• Flash Point: 192.2°C
• Density: 1.21g/cm³
• Vapor Pressure: 2.03E-06mmHg at 25°C
• Refractive Index: 1.647
• CAS DataBase Reference: 6-({[2-(methylsulfanyl)phenyl]amino}methylidene)cyclohexa-2,4-dien-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-({[2-(methylsulfanyl)phenyl]amino}methylidene)cyclohexa-2,4-dien-1-one(19850-36-3)
• EPA Substance Registry System: 6-({[2-(methylsulfanyl)phenyl]amino}methylidene)cyclohexa-2,4-dien-1-one(19850-36-3)

Safety Data

• Hazardous Substances Data: 19850-36-3(Hazardous Substances Data)

Upstream product

• 2987-53-3 2-(Methylthio)aniline 
• 90-02-8 salicylaldehyde 

Downstream Products

• 1426330-56-4 C₃₄H₃₈N₂O₄S₂Ti 

Relevant articles and documents

ONS-donor ligand based Pt(II) complexes display extremely high anticancer potency through autophagic cell death pathway

The current study unveils ONS-donor ligand based Pt(II) complexes with unusual anticancer potency showing higher anticancer effect as compared to cisplatin. This series of Pt(II)(R-salicylaldimine)Cl (C1a-C4a) (R = 5-H, 5-CH3, F, 3-CH3/su

Copper(II) and palladium(II) complexes with tridentate NSO donor Schiff base ligand: Synthesis, characterization and structures

Mononuclear copper(II) complex [CuL2] and palladium(II) complexes [Pd(X)L] where X?=?benzoate(bz) or salicylate(sal) and HL?=?2-(methylthio)phenylimino)methyl)phenol, a Schiff base ligand with NSO coordination sites have been synthesized and characterized by microanalyses, IR, UV–Visible spectra, conductivity measurement and magnetic studies. Crystal structures of all the complexes have been solved by single crystal X-ray diffraction studies and showed that there are two molecules in a unit cell in the [CuL2] complex - one molecule has square planar geometry whereas second molecule has distorted square pyramidal geometry and palladium(II) complexes have distorted square planar geometry.

Ruthenium complexes bearing tridentate 2-(methylthio)phenylsalicylaldimine Schiff-base ligands

Reaction of [Ru(PPh3)3Cl2] with 2-(methylthio)phenylsalicylaldimine Schiff-base (HL) in tetrahydrofuran (THF) in the presence of triethylamine afforded a ruthenium(II) complex [Ru(ONS-L)(PPh3)2Cl]·CH3OH·2.75H2O (1). Similarly, reaction of [Ru(CO)2Cl2] with HL in N,N′-dimethylformamide (DMF) in the presence of triethylamine gave a ruthenium(II) complex [Ru(ONS-L)(CO)2Cl] (2), while the reaction between [Ru(CO)2Cl2] and HL without base resulted in a ruthenium(III) complex [Ru(ONS-L)(CO)Cl2] (3). Treatment of RuCl3·3H2O with HL in ethanol in the presence of triethylamine gave an anionic complex [Et3NH][Ru(ONS-L)Cl3] (4), which reacted with [Cp?2Ru] in the presence of sodium hydroxide to give complex [Cp?Ru(η6-1,2,3,4-Me4C6H2)][Ru(ONS-L)Cl3]·CH2Cl2 (5) with a different cation. Besides, reaction of 4 and AgNO3 afforded a dinuclear ruthenium(II) complex [Ru2(ONS-L)(μ-ONS-L)2Cl]·CH2Cl2 (6). The structures of complexes 1–6 have been established by X-ray crystallography, of which complex 4 was selected as a catalyst for the typical oxidation of 1-phenylethanol to the according acetophenone.

Antitumor-activity Pt(II) coordination compound with ONS tridentate ligand as well as preparation method and application thereof

The invention belongs to the technical field of biological medicines, and particularly relates to an antitumor-activity Pt(II) coordination compound with an ONS tridentate ligand as well as a preparation method and application thereof. The antitumor-activity Pt(II) coordination compound with the ONS tridentate ligand, which is provided by the invention, is of a plane-quadrangle coordination structure; Pt(II) is coordinated with a tridentate (ONS) salicylaldimine derivative ligand and one 4-methylpyridine or halogen ligand. Verified through the growth inhibition test of an in-vitro tumor cell, compared with cis-platinum, the coordination compound made by the preparation method shows higher antitumor activity in cancer cells of a nonsmall-cell lung cancer (NSCLC), a colorectal cancer (CRC), a mammary cancer and the like; the coordination compound has an IC50 value which reaches 0.13 to 6.25 microns, and can be used for preparing a medicine for treating a cancer.

The enhanced catalytic performance of cobalt catalysts towards butadiene polymerization by introducing a labile donor in a salen ligand

A family of cobalt complexes supported by a tridentate Schiff base ligand with a labile donor (O, S, N) as a pendant arm (Co1-Co12, formulated as CoL 2) were synthesized by the treatment of the corresponding ligands with cobalt acetate tetrahyd

Sodium cubane and double-cubane aggregates of hybridised salicylaldimines and their transmetallation to nickel for catalytic ethylene oligomerisation

Deprotonation of functional salicylaldimines with NaH invariably results in cubane or double-cubane Na(i) aggregates which transmetallate with Ni(ii) under different stoichiometric conditions to give Ni(ii) complexes that are catalytically active towards

Synthesis, characterization, and catalytic activity of titanium iminophenoxide complexes in relation to the ring-opening polymerization of L -lactide and ε-caprolactone

This study synthesized a series of titanium iminophenoxide complexes and investigated their suitability as catalysts for the ring-opening polymerization of L-lactide (L-LA) and ε-caprolactone (CL). Complexes with bidentate ligands demonstrate higher catal

Synthesis, characterization and catalytic activity of lithium and sodium iminophenoxide complexes towards ring-opening polymerization of L-lactide

A series of lithium and sodium iminophenoxide complexes have been successfully synthesized and characterized by X-ray crystallography and investigated as catalysts for the ring opening polymerization of L-lactide. The nature and steric bulk of the ligands coordinated to the central metal ions greatly influence the catalytic properties. Complexes with bidenate ligands exhibit higher catalytic activity than tridentate counterparts because the third coordination atom contends with L-lactide, which decreases activity. Oxygen is the third atom in the tridentate ligand, providing stronger chelation ability with Li and Na than nitrogen or sulfur and occupies the space with which L-lactide is coordinated. The Royal Society of Chemistry 2012.