199192-10-4

Basic information

• Product Name: Ethanone, 1-(2,3-dihydro-1H-pyrrolizin-7-yl)- (9CI)
• Synonyms: Ethanone, 1-(2,3-dihydro-1H-pyrrolizin-7-yl)- (9CI)
• CAS NO: 199192-10-4
• Molecular Formula: C9H11NO
• Molecular Weight: 149.18974
• Product Categories: ACETYLGROUP
• Mol File: 199192-10-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 1-(2,3-dihydro-1H-pyrrolizin-7-yl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2,3-dihydro-1H-pyrrolizin-7-yl)- (9CI)(199192-10-4)
• EPA Substance Registry System: Ethanone, 1-(2,3-dihydro-1H-pyrrolizin-7-yl)- (9CI)(199192-10-4)

Safety Data

• Hazardous Substances Data: 199192-10-4(Hazardous Substances Data)

Upstream product

• 1072-82-8 3-acetylpyrrole 

Relevant articles and documents

Bu3SnH mediated oxidative radical cyclisation onto imidazoles and pyrroles

A new protocol using radical cyclisation has been developed for the synthesis of [1,2-c]-fused imidazoles and [1,2-a]-fused pyrroles. The intermediate nucleophilic N-alkyl radicals, generated using Bu3SnH from N- (ω-bromoalkyl) or N-[ω-(phenylselanyl)alkyl] imidazoles and pyrroles, undergo regio-selective radical cyclisalion onto the azole rings followed by oxidative re-aromatisation.

Oxidative radical cyclisations onto imidazoles and pyrroles using Bu3SnH

Oxidative radical cyclisation using Bu3SnH has been used for the synthesis of [1,2-c]-fused imidazoles and [1,2-a]-fused pyrroles from imidazolecarbaldehydes and acylpyrroles respectively. The intermediate nucleophilic N-alkyl radicals cyclise onto imidazole and pyrrole rings followed by oxidative re-aromatisation.