Synthesis and evaluation of enantiomeric purity of protected α-amino and peptide aldehydes
The synthesis of enantiomerically pure Ac-Tyr-Val-Ala-Asp(O'Bu)-H dimethyl acetal ((S)-1) is reported, a protected tetrapeptide C-terminal aldehyde belonging to a class of potent, reversible inhibitors of cysteine proteases (e.g., interleukin-1β-convertin
Mindt, Thomas,Michel, Urs,Dick
p. 1960 - 1968
(2007/10/03)
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