199659-23-9 Usage
Uses
Used in Pharmaceutical Industry:
5-Chlorothiophene-3-boronic acid is used as a synthetic reagent for the preparation of pyrazolyl-tetrahydropyran calcium channel blockers. These blockers play a crucial role in pain therapy, as they help in the regulation of calcium ion flow through calcium channels, which is essential for the proper functioning of the nervous system and the transmission of pain signals.
In the synthesis of these calcium channel blockers, 5-chlorothiophene-3-boronic acid serves as a key building block, providing the necessary structural features that enable the development of effective pain relief medications. Its reactivity and compatibility with various synthetic routes make it a valuable component in the design and production of novel therapeutic agents for the treatment of pain and related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 199659-23-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,6,5 and 9 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 199659-23:
(8*1)+(7*9)+(6*9)+(5*6)+(4*5)+(3*9)+(2*2)+(1*3)=209
209 % 10 = 9
So 199659-23-9 is a valid CAS Registry Number.
InChI:InChI=1/C4H4BClO2S/c6-4-1-3(2-9-4)5(7)8/h1-2,7-8H
199659-23-9Relevant articles and documents
PYRIDINE DERIVATIVES AND APPLICATION OF ANTI-MACOBACTERIUM THEREOF
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Paragraph 0250; 0251, (2016/10/08)
The present invention provides a series of pyridine derivatives and their preparation method and application thereof. The series of pyridine derivatives can be applied to treating mycobacterium-related diseases, especially to treatments of fatal mycobacterium-related diseases. The fatal diseases may be related to mycobacterium tuberculosis, mycobacterium bovis, mycobacterium avium, and mycobacterium marinum.
HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE
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Page/Page column 62, (2011/10/05)
The present invention relates to compounds and methods which may be useful as inhibitors of H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.
