- Carbon tetrabromide mediated oxidative cyclocondensation of ketones and thioureas: An easy access to 2-aminothiazoles
-
A simple, mild, and efficient one-pot method for the synthesis of substituted 2-aminothiazoles has been reported. The reaction involves the formation of sulfenyl bromide as an umpolung intermediate of nucleophilic sulfur, which is responsible for C-S bond formation leading to oxidative cyclization of ketones and thioureas to furnish the desired products. Carbon tetrabromide was used as a convenient and mild brominating reagent under basic condition at room temperature to give 2-aminothiazoles in good to excellent yields.
- Keshari, Twinkle,Kapoorr, Ritu,Yadav, Lal Dhar S.
-
supporting information
p. 5623 - 5627
(2015/09/21)
-
- A simple, three-component synthesis of 2-aminothiazoles using trimethylsilyl isothiocyanate
-
The first multicomponent, solution-phase protocol to prepare privileged 2-aminothiazoles from α-bromocarbonyl compounds and amines (aromatic and aliphatic) using commercially available trimethylsilyl isothiocyanate is described.
- Golubev, Viktor,Zubkov, Fedor,Krasavin, Mikhail
-
p. 4844 - 4847
(2013/08/28)
-
- Synthesis and Characterization of 1,3-Bis-(2-dialkylamino-5-thiazolyl)-Substituted Squaraines and Their 2-(Dialkylamino)thiazole Precursors
-
By condensation of squaric acid (1) with 2-(dialkylamino)-substituted thiazoles 8 a novel type of heterocyclic-substituted squaraines of the general structure 9 was prepared in moderate yield mostly.The squaraines 9 obtained are sparingly soluble in the most organic solvents and exhibit, in these solvents, narrow absorption bands in the visible range at about 620-700 nm.In dispersed form, the absorption bands of the squaraines 9 are, however, broadened and shifted into the NIR region at about 900 nm.These unique properties of the new squaraines 9 suggest the use of these dyes as spectral sensitizers for laser-driven data recording or data storage media. - Key Words: Squaraines/ Squaric acid/ Thiazoles/ Sensitizers
- Keil, D.,Hartmann, H.
-
p. 979 - 984
(2007/10/02)
-
- Substituted 2-Aminothiazoles from α-Thiocyanato-acetophenones and Dialkylamines
-
α-Thiocyanato-acetophenones 1 react with dialkylammonium salts of weak acids (acetates, propionates, benzoates) to give 2-dialkylamino-4-aryl-thiazoles 4.As reaction medium aliphatic alcohols (methanol, ethanol), dipolar-aprotic solvents (acetonitrile, di
- Teller, J.,Dehne, H.,Zimmermann, T.,Fischer, G. W.,Olk, B.
-
p. 453 - 460
(2007/10/02)
-