200554-19-4

Basic information

• Product Name: Alexa Fluor 350
• Synonyms: Alexa Fluor 350
• CAS NO: 200554-19-4
• Molecular Formula: C₁₆H₁₄N₂O₉S
• Molecular Weight: 410.36
• Mol File: 200554-19-4.mol

Chemical Properties

• Appearance: /
• Density: 1.74±0.1 g/cm3(Predicted)
• Solubility: Soluble in water, dimethyl sulfoxide, methanol
• PKA: 0.46±0.20 Most Basic Temperature: 25°C
• CAS DataBase Reference: Alexa Fluor 350(CAS DataBase Reference)
• NIST Chemistry Reference: Alexa Fluor 350(200554-19-4)
• EPA Substance Registry System: Alexa Fluor 350(200554-19-4)

Safety Data

• Hazardous Substances Data: 200554-19-4(Hazardous Substances Data)

Upstream product

• 105832-38-0 O-(N-succinimidyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate 
• 113721-84-9 7-carboethoxyamido-4-methylcoumarin-3-acetic acid ethyl ester 

Relevant articles and documents

7-amino-4-methyl-6-sulfocoumarin-3-acetic acid: A novel blue fluorescent dye for protein labeling

7-Amino-4-methyl-6-sulfocoumarin-3-acetic acid (AMCA-S, also called Alexa(TM) 350) 2 was synthesized as a new water-soluble blue fluorescent dye for protein labeling. Compared with its nonsulfonated counterpart (AMCA) 1 the new dye gave significantly higher fluorescence quantum yields on proteins.

Sulfonated derivatives of 7-aminocoumarin

The present invention describes 7-aminocoumarin dyes that are substituted one or more times at the 3-, 6- and/or 8-positions by a sulfonic acid or a salt of a sulfonic acid, said dyes being useful as fluorescent probes or in the preparation of enzyme substrates, caged probes, or adducts with reducing sugars. The dyes of the invention optionally possess a reactive group useful for preparing fluorescent conjugates, which conjugates and methods for their preparation are described herein.