201470-17-9

Basic information

• Product Name: Ethanone, 2-bromo-1-(5-thiazolyl)- (9CI)
• Synonyms: Ethanone, 2-bromo-1-(5-thiazolyl)- (9CI);2-BroMo-1-(thiazol-5-yl)ethanone;5-(2-Bromoacetyl)thiazole;Ethanone, 2-bromo-1-(5-thiazolyl)-
• CAS NO: 201470-17-9
• Molecular Formula: C₅H₄BrNOS
• Molecular Weight: 206.06036
• Product Categories: ACETYLHALIDE
• Mol File: 201470-17-9.mol

Chemical Properties

• Boiling Point: 276.5±15.0 °C(Predicted)
• Appearance: /
• Density: 1.763±0.06 g/cm3(Predicted)
• PKA: 0.28±0.10(Predicted)
• CAS DataBase Reference: Ethanone, 2-bromo-1-(5-thiazolyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-bromo-1-(5-thiazolyl)- (9CI)(201470-17-9)
• EPA Substance Registry System: Ethanone, 2-bromo-1-(5-thiazolyl)- (9CI)(201470-17-9)

Safety Data

• Hazardous Substances Data: 201470-17-9(Hazardous Substances Data)

Upstream product

• 91516-28-8 1-(thiazol-5-yl) ethan-1-one 

Downstream Products

• 917904-58-6 2-{2-[3-(3-Morpholin-4-yl-propoxy)-phenyl]-pyrrolidin-1-yl}-1-thiazol-5-yl-ethanone 

Relevant articles and documents

SUBSTITUTED IMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted imidazole carboxamides and related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat a medical disorder, e.g., cancer, lysosomal storage disorder, neurodegenerative disorder, inflammatory disorder, in a patient.

A 2-amino-thiazole compounds (by machine translation)

The present invention relates to the technical field of pharmaceutical chemistry, particularly relates to a 2-amino thiazole compound or its pharmaceutically acceptable salts, its preparation method, and pharmaceutical compositions containing such compounds and its application in the preparation of antineoplastic. (by machine translation)

Pyrrolidino-tetrahydroisoquinolines bearing pendant heterocycles as potent dual H3 antagonist and serotonin transporter inhibitors

A series of novel and potent 6-heteroaryl-pyrrolidino-tetrahydroisoquinolines with dual histamine H3 antagonist/serotonin transporter inhibitor activity is described. In vitro and in vivo data are discussed.

SUBSTITUTED SULFONAMIDES AS SELECTIVE BETA-3 AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY

Substituted sulfonamides are selective β 3 adrenergic receptor agonists with very little β 1 and β 2 adrenergic receptor activity and as such the compounds are capable of increasing lipolysis and energy expenditure in cells. The compounds thus have potent activity in the treatment of Type II diabetes and obesity. The compounds can also be used to lower triglyceride levels and cholesterol levels or raise high density lipoprotein levels or to decrease gut motility. In addition, the compounds can be used to reduced neurogenic inflammation or as antidepressant agents. The compounds are prepared by coupling an aminoalkylphenyl-sulfonamide with an appropriately substituted epoxide. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for increasing gut motility are also disclosed.