- Isotope-Coded Maleimide Affinity Tags for Proteomics Applications
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Isotope-coded affinity tags (ICATs) are valuable tools for mass spectrometry-based quantitative proteomics, in particular, for comparison of protein (cysteine-residue) thiol oxidation state in normal, stressed, and diseased tissue. However, the iodoacetam
- Wdowiak, Adam P.,Duong, Marisa N.,Joyce, Rohan D.,Boyatzis, Amber E.,Walkey, Mark C.,Nealon, Gareth L.,Arthur, Peter G.,Piggott, Matthew J.
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p. 1652 - 1666
(2021/07/20)
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- Synthesis of deleobuvir, a potent hepatitis C virus polymerase inhibitor, and its major metabolites labeled with carbon-13 and carbon-14
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Deleobuvir, (2E)-3-(2-{1-[2-(5-bromopyrimidin-2-yl)-3-cyclopentyl-1-methyl-1H-indole-6-carboxamido]cyclobutyl}-1-methyl-1H-benzimidazol-6-yl)prop-2-enoic acid (1), is a non-nucleoside, potent, and selective inhibitor of hepatitis C virus NS5B polymerase.
- Latli, Bachir,Hrapchak, Matt,Chevliakov, Maxim,Li, Guisheng,Campbell, Scot,Busacca, Carl A.,Senanayake, Chris H.
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p. 250 - 260
(2015/06/16)
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