Lewis acid catalyst free synthesis of benzimidazoles and formamidines in 1,1,1,3,3,3-hexafluoro-2-propanol
A simple, inexpensive, environmentally friendly and efficient route for the synthesis of benzimidazole and formamidine derivatives by the reaction of O-phenylenediamines or amines with orthoesters using hexafluoroisopropanol as a solvent/catalyst is described.
Khaksar, Samad,Heydari, Akbar,Tajbakhsh, Mahmood,Vahdat, Seyed Mohammad
experimental part
p. 1377 - 1381
(2011/02/22)
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