201811-20-3 Usage
Uses
Used in Food Industry:
BHA is used as a preservative in the food industry to prevent the oxidation of fats and oils, thereby extending the shelf life of products. It helps maintain the freshness and quality of food items, such as snacks, cereals, and cooking oils.
Used in Cosmetics Industry:
In the cosmetics industry, BHA is used as an antioxidant to prevent the oxidation of ingredients, ensuring the stability and longevity of cosmetic products. It helps protect the products from spoilage and degradation, maintaining their efficacy and quality.
Used in Pharmaceutical Industry:
BHA is utilized in the pharmaceutical industry as an antioxidant to protect medications from oxidation, ensuring their stability and potency. It helps maintain the quality and effectiveness of pharmaceutical products, contributing to their safety and efficacy.
Due to concerns about the potential health effects of BHA, its usage in food products is regulated in some countries, and there is an ongoing search for alternative natural antioxidants to replace it.
Check Digit Verification of cas no
The CAS Registry Mumber 201811-20-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,8,1 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 201811-20:
(8*2)+(7*0)+(6*1)+(5*8)+(4*1)+(3*1)+(2*2)+(1*0)=73
73 % 10 = 3
So 201811-20-3 is a valid CAS Registry Number.
201811-20-3Relevant articles and documents
FGFR INHIBITORS FOR THE TREATMENT OF CANCER
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Paragraph 00173; 00174, (2020/08/28)
The disclosure provides novel FGFR inhibitors based on the pyridinylpyrimidine. The disclosure includes inhibitors with broad inhibitory activity against all FGFR isoforms, and inhibitors with selective inhibition against FGFR4. These novel pyridinylpyrimidine-based FGFR inhibitors, or their derivatives, have strong potential to be used to treat cancer.
Design, synthesis and SAR of novel ethylenediamine and phenylenediamine derivatives as factor Xa inhibitors
Yoshikawa, Kenji,Yoshino, Toshiharu,Yokomizo, Yoshihiro,Uoto, Kouichi,Naito, Hiroyuki,Kawakami, Katsuhiro,Mochizuki, Akiyoshi,Nagata, Tsutomu,Suzuki, Makoto,Kanno, Hideyuki,Takemura, Makoto,Ohta, Toshiharu
, p. 2133 - 2140 (2011/04/24)
We previously reported on a series of cyclohexanediamine derivatives as highly potent factor Xa inhibitors. Herein, we describe the modification of the spacer moiety to discover an alternative scaffold. Ethylenediamine derivatives possessing a substituent at the C1 position in S configuration and phenylenediamine derivatives possessing a substituent at the C5 position demonstrated moderate to strong anti-fXa activity. Further SAR studies led to the identification of compound 30h which showed both good in vitro activity (fXa IC50 = 2.2 nM, PTCT2 = 3.9 μM) and in vivo antithrombotic efficacy.
