- Selexipag intermediates and method for preparing selexipag
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The invention belongs to the field of chemical preparation, and relates to selexipag intermediates and a method for preparing selexipag. The selexipag intermediates are a compound SLP-4, a compound SLP-7, a compound SLP-8 and a compound SLP-10. The selexipag intermediates and the method have the advantages that the method for preparing the selexipag includes reasonable routes and is low in cost and operative difficulty and little in environmental pollution, raw materials are easily available, accordingly, requirements of large-scale industrial production can be met by the method, and the like.
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Paragraph 0063; 0108; 0109; 0110; 0111; 0112
(2017/08/27)
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- PROCESSES FOR PREPARATION OF SELEXIPAG AND ITS AMORPHOUS FORM
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The present application relates to processes for preparation of Selexipag, its amorphous form, amorphous solid dispersion and pharmaceutical composition thereof. Formula (I):
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Page/Page column 19
(2017/03/14)
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- Use of acylsulfonamido-substituted polymethine dyes as fluorescene dyes and/or markers
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The invention relates to a novel polymethine dyes containing at least one acylsulfonamido group of the formula (I) in which n, Y, A and R have the meaning given in the claims, and at least one compound of the formulae (a) to (n) given in the claims. The polymethine dyes according to the invention are suitable for use as dyes and/or labels, in particular for staining or labeling biomolecules.
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Page/Page column 63
(2008/06/13)
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