- Two new glycosides from Sanicula lamelligera
-
Two new glycosides, 21-O-β-D-glucopyranosyl-olean-12-ene-3β, 16α, 21β, 22α, 28-pentol-3-O-β-D-glucopyranosyl (1 → 2)-[β-D-arabinopyranosyl (1 → 3)]-β-D-glucopyranoside-(1) and 4-O-β-D-glucopyranosyl rosmarinic acid (3), along with the known compound rosmarinic acid (2) were isolated from the whole plants of Sanicula lamelligera Hance. Their structures were elucidated by spectroscopic analysis and chemical means.
- Zhou, Ling-Yun,Liu, Hai-Yang,Xie, Bai-Bo,Liu, Zhi-Hai,Chen, Chang-Xiang
-
p. 607 - 610
(2008/01/27)
-
- Bryophyte constituents; 7: New synthesis of (+)-rosmarinic acid and related compounds
-
Efficient and expeditious syntheses are described for rosmarinic acid (1) and its derivatives 2-4, making extensive use of allyl protective groups for both carboxylic acids and phenolic building blocks. (+)(R)-Rosmarinic acid was obtained by a chemoenzymatic resolution of its phenyl lactic acid precursors.
- Eicher, Theophil,Ott, Markus,Speicher, Andreas
-
p. 755 - 762
(2007/10/03)
-
- Chemo-enzymatic synthesis of rosmarinic acid
-
(R)-(+)-3-(3,4-Dihydroxyphenyl)lactic acid was produced in an enzyme membrane reactor with an optical purity higher than 99percent.Complete reactor modelling of the process was done and the theoretically evaluated data was verified by a continuous experiment with space-time yields more than 1000 g/(l*d).For the sythesis of CoA-activated caffeic acid, a new method was found to prepare the ester via the caffeic acid imidazolide.In a batch experiment, it was shown that enzymatically prepared (R)-(+)-3-(3,4-dihydroxyphenyl)lactic acid and chmically synthesized CoA caffeic ester w ere converted to rosmarinic acid by an enzyme isolated from Coleus blumei cell cultures.
- Pabsch, K.,Petersen, M.,Rao, N. N.,Alfermann, A. W.,Wandrey, C.
-
p. 199 - 205
(2007/10/02)
-
