203731-15-1

Basic information

• Product Name: Phenol, 2-[(E)-(methyloxidoimino)methyl]- (9CI)
• Synonyms: Phenol, 2-[(E)-(methyloxidoimino)methyl]- (9CI)
• CAS NO: 203731-15-1
• Molecular Formula: C8H9NO2-
• Molecular Weight: 151.16256
• Product Categories: ALCOHOL
• Mol File: 203731-15-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Phenol, 2-[(E)-(methyloxidoimino)methyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-[(E)-(methyloxidoimino)methyl]- (9CI)(203731-15-1)
• EPA Substance Registry System: Phenol, 2-[(E)-(methyloxidoimino)methyl]- (9CI)(203731-15-1)

Safety Data

• Hazardous Substances Data: 203731-15-1(Hazardous Substances Data)

Upstream product

• 89-95-2 2-methyl-benzyl alcohol 
• 4229-44-1 N-methylhydroxyamine hydrochloride 
• 180265-66-1 2-((hydroxy(methyl)amino)methyl)phenol 
• 90-02-8 salicylaldehyde 

Relevant articles and documents

Synthesis and application of phenyl Nitrone derivatives as acidic and microbial corrosion inhibitors

Nitrone has drawn great attention due to its wide applications as a 1,3-dipole in heterocyclic compounds synthesis and the bioactivities. With the special structure, nitrone can also be used as ligand in inorganic chemistry. Based on the current research,

A facile and new method for the synthesis of α-aryl-N-methylnitrones in solvent-free media using silica gel-NaOH

Substituted α-aryl-N-methylnitrones are prepared by the condensation reaction of N-methylhydroxylamine hydrochloride and benzaldehydes in solvent-free media using silica-gel-NaOH catalyst system. The yields are excellent regardless of the electron-donatin

An efficient and rapid chemoselective synthesis of α-Aryl-N-methylnitrones in dry media

A simple, efficient, and eco-friendly procedure was developed for the condensation of N-methylhydroxylamine hydrochloride with benzaldehydes bearing electron-donating or electron-withdrawing substituents in the presence of powdered molecular sieves (3 A)

Oxidation of N-benzyl-N-methylhydroxylamines to nitrones. A mechanistic study

Oxidation of various N-(o-, m-, p- substituted benzyl)- N-methylhydroxylamines has been carried out using mercury(II) oxide and p-benzoquinone (p-BQ) as oxidants. Hammett plots have been obtained with negative ρ values, showing the development of a positive centre in the transition state. The unstable E nitrones, which readily isomerize to the more stable Z nitrones, are obtained in appreciable quantities and in some cases as the major product. A considerable deuterium isotope effect is observed in the oxidation process. The overall picture of the mechanistic pathway involves electron transfer from nitrogen to the oxidant followed by hydrogen abstraction.

Nitrogen inversion and N-O bond rotation processes in di- and tri-substituted hydroxylamines. A dynamic NMR study

The barriers to inversion in several acyclic di- and tri-substituted hydroxylamines are determined by 1H NMR band shape analysis.The barriers range from 49.1 to 66.8 kJ mol1- and are discussed in terms of a conformational process which involves nitrogen inversion and rotation around the N-O bond.The N-benzyl group with an ortho hydroxy substituent increases the nitrogen inversion barrier by 10 kJ mol-1, which indicates the requirement of breaking of the intramolecular hydrogen bond prior to inversion.