The synthesis of (±)-aminoglutethimide via vicarious nucleophilic aromatic substitution of hydrogen
The synthesis of aminoglutethimide via a one-pot coupling of nitrobenzene, ethyl 2-chlorobutyrate and 3-bromopropionitrile has been achieved via a process involving sequential vicarious nucleophilic aromatic substitution and alkylation.
Bushell, Simon M.,Crump, J. Paul,Lawrence, Nicholas J.,Pineau, Guillaume
p. 2269 - 2274
(2007/10/03)
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