204068-72-4

Basic information

• Product Name: 2-Thiophenecarboxylicacid,5-amino-
• Synonyms: 2-Thiophenecarboxylicacid,5-amino-;2-Thiophenecarboxylicacid,5-amino-(9CI);5-amino-2-Thiophenecarboxylic acid
• CAS NO: 204068-72-4
• Molecular Formula: C5H5NO2S
• Molecular Weight: 143.1637
• Product Categories: AMINEPRIMARY;AMINOACID;CARBOXYLICACID
• Mol File: 204068-72-4.mol

Chemical Properties

• Boiling Point: 385.561°C at 760 mmHg (Cal.) ref.
• Flash Point: 186.981°C (Cal.) ref.
• Appearance: /
• Density: 1.527g/cm3 (Cal.) ref.
• CAS DataBase Reference: 2-Thiophenecarboxylicacid,5-amino-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiophenecarboxylicacid,5-amino-(204068-72-4)
• EPA Substance Registry System: 2-Thiophenecarboxylicacid,5-amino-(204068-72-4)

Safety Data

• Hazardous Substances Data: 204068-72-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Thiophenecarboxylic acid, 5-aminois used as a building block for the synthesis of various organic compounds in the pharmaceutical industry. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Thiophenecarboxylic acid, 5-aminois used as a building block for the synthesis of various organic compounds with potential applications in crop protection and pest control.
Used in Fine Chemicals Production:
2-Thiophenecarboxylic acid, 5-aminois used as an intermediate in the production of dyes, pigments, and other fine chemicals due to its unique chemical properties and reactivity.
Used in Drug Discovery and Development:
Due to its biological activity, 2-Thiophenecarboxylic acid, 5-aminois a potential candidate for drug discovery and development. It can be further modified and optimized to develop new drugs with improved efficacy and safety profiles.

Upstream product

• 154308-84-6 allyl 5-nitro-2-thiophenecarboxylate 

Relevant articles and documents

Antibiotic penem compounds

The present invention provides a compound of the formula (I) STR1 wherein: R1 is 1-hydroxyethyl, 1-fluoroethyl or hydroxymethyl; R2 is hydrogen or C1-4 alkyl; Z is carboxy, sufonic acid, tetrazol-5-yl or C 1-4 alkylsulfonylcarbamoyl (--CONHSO2 C1-4 alkyl); A is a phenyl or thienyl ring; and A is optionally further substituted by one or two substituents or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof. Processes for their preparation, intermediates in their preparation, their use as therapeutic agents and pharmaceutical compositions containing them.

Disubstituted aryl and heteroaryl imines having retinoid-like biological activity

Compounds of the formula STR1 wherein the R 1 groups independently are hydrogen, lower alkyl, or two geminal R 1 groups jointly represent an oxo ( O) or a thio ( S) group; R 2 is hydrogen or lower alkyl, or halogen; M is or --N CR 4 -- or --R 4 C N-- where R 4 is hydrogen or lower alkyl; X is C(R 1) 2 ; Y is phenyl optionally substituted with an R 3 group which is lower alkyl or halogen; A is (CH 2) n where n is 0-5, lower branched chain alkyl, cycloalkyl, alkenyl, alkynyl; B is hydrogen, COOH or a pharmaceutically acceptable salt thereof, COOR 8, CONR 9 R 10, --CH 2 OH, CH 2OR 11, CH 2 OCOR 11, CHO, CH(OR 12) 2, CHOR 13 O, --COR 7, CR 7 (OR 12) 2, or CR 7 OR 13 O, where R 7 is an alkyl, cycloalkyl or alkenyl group containing 1 to 5 carbons, R 8 is an alkyl group of 1 to 10 carbons, or a cycloalkyl group of 5 to 10 carbons, or R 8 is phenyl or lower alkylphenyl, R 9 and R 10 independently are hydrogen, an alkyl group of 1 to 10 carbons, or a cycloalkyl group of 5-10 carbons, or phenyl or lower alkylphenyl, R 11 is lower alkyl, phenyl or lower alkylphenyl, R 12 is lower alkyl, and R 13 is divalent alkyl radical of 2-5 carbons have retinoid-like biological activity.