Synthesis of fluorinated enynes and dienes via 1-bromo 2-fluoro alkenes
A stereospecific synthesis of fluorinated enynes and dienes was performed through palladium-catalyzed condensation of 1-bromo-2-fluoroalkenes, synthesized either through 'BrF' addition to the corresponding alkynes or through bromine addition and HBr elimi
Eddarir,Mestdagh,Rolando
p. 69 - 72
(2007/10/02)
INVESTIGATION OF LIGNIFICATION BY MEANS OF FLUORINATED ANALOGUES OF FERULIC ACID AND CONIFERYL ALCOHOL
Nicotiana tabacum; Solanaceae; tobacco; oxidation; peroxidase; fluorinated cinnamic compounds; lignin. 2-Fluoro-analogues of ferulic acid and coniferyl alcohol were synthesized from vanillin acetate.These new compounds were used as hydrogen donors by tobacco peroxidases, giving rise to lignin-like compounds.In the presence of standard peroxidase substrates, the flurinated analogues behaved as competitive inhibitors and could therefore be used both in vivo and in vitro as antimetabolites of peroxidase-catalysed reactions.